Diaryl Urea Derivative Molecule Inhibits Cariogenic Streptococcus mutans by Affecting Exopolysaccharide Synthesis, Stress Response, and Nitrogen Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.904488
Abstract: Different small molecules have been developed to target cariogenic bacteria Streptococcus mutans. Based on target-based designing and in silico screening, a novel diaryl urea derivative, 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea (BPU), has previously been found effective in inhibiting the… read more here.
Keywords: urea derivative; stress response; streptococcus mutans; molecule ... See more keywords
Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety
Sign Up to like & getrecommendations! Published in 2018 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.220971
Abstract: Diaryl urea derivatives have exhibited a broad spectrum of biochemical effects and pharmaceutical applications. Several diaryl urea derivatives such as sorafenib, regorafenib, linifanib, and tivozanib and lenvatinib are in clinical trial or clinical use. Therefore,… read more here.
Keywords: urea derivatives; quinoxalindione moiety; diaryl urea; synthesis characterization ... See more keywords