1,6-Aza-Michael addition of para-quinone methides with N-heterocycles catalyzed by Zn(OTf)2: A regioselective approach to N-diarylmethyl-substituted heterocycles
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DOI: 10.1016/j.tet.2020.131338
Abstract: Abstract An efficient Zn(OTf)2-catalyzed regioselective C–N bond making reaction between a bunch of aryl/heteroaryl-substituted para-quinone methides as ideal 1,6-acceptors and various aromatic/non-aromatic aza-heterocycles bearing N–H moiety namely carbazoles, pyrazoles, indazole, benzotriazole and saccharin is reported.… read more here.
Keywords: quinone methides; michael addition; para quinone; diarylmethyl substituted ... See more keywords