Enhancement of toyocamycin production through increasing supply of precursor GTP in Streptomyces diastatochromogenes 1628.
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DOI: 10.1002/jobm.202100622
Abstract: The nucleoside antibiotic toyocamycin (TM), which is produced by Streptomyces diastatochromogenes 1628, exhibits potent activity against a broad range of phytopathogenic fungi. TM was synthesized through a multi-step reaction, using guanosine triphosphate (GTP) as precursor.… read more here.
Keywords: precursor; gtp; production; toyocamycin ... See more keywords
AdpAsd, a Positive Regulator for Morphological Development and Toyocamycin Biosynthesis in Streptomyces diastatochromogenes 1628
Sign Up to like & getrecommendations! Published in 2018 at "Current Microbiology"
DOI: 10.1007/s00284-018-1529-6
Abstract: AdpA is studied and considered as a pleiotropic regulator which is involved in morphological development and secondary metabolism in many Streptomyces. In this study, AdpAsd, which was cloned from toyocamycin (TM)-producing strain Streptomyces diastatochromogenes 1628,… read more here.
Keywords: biosynthesis; 1628 t62; morphological development; diastatochromogenes 1628 ... See more keywords