Diastereo- and Enantioselective Metathesis Dimerization/Kinetic Resolution of Racemic Planar-Chiral Vinylferrocenes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02888
Abstract: Diastereo- and enantioselective kinetic resolution of racemic planar-chiral 1-R-2-vinylferrocenes (rac-1) was attained by the molybdenum-catalyzed asymmetric metathesis dimerization (AMD). Two sequential AMD reactions of rac-1a (R = Br) provided (E)-(S,S)-1,2-di(2-bromoferrocenyl)ethylene in >99% ee, which was… read more here.
Keywords: racemic planar; diastereo enantioselective; resolution racemic; planar ... See more keywords
Highly Diastereo- and Enantioselective Ir-Catalyzed Hydrogenation of 2,3-Disubstituted Quinolines with Structurally Fine-Tuned Phosphine-Phosphoramidite Ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b03925
Abstract: A highly diastereo- and enantioselective Ir-catalyzed hydrogenation of unfunctionalized 2,3-disubstituted quinolines, especially 3-alkyl-2-arylquinolines, has been realized. The success of this hydrogenation is ascribed to the use of a structurally fine-tuned chiral phosphine-phosphoramidite ligand with a… read more here.
Keywords: highly diastereo; hydrogenation; catalyzed hydrogenation; diastereo enantioselective ... See more keywords
Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones
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DOI: 10.1038/s41467-017-01451-1
Abstract: Optically active spirocyclic compounds play an important role in drug discovery, and new synthetic strategies for the efficient generation of spiro stereocenters are in much demand. Here we report a catalytic enantioselective cycloaddition using spirocyclic… read more here.
Keywords: enantioselective cycloaddition; cycloaddition spirocyclopropyl; diastereo enantioselective; spirocyclopropyl oxindoles ... See more keywords
Diastereo- and enantioselective phase-transfer alkylation of 3-substituted oxindoles with racemic secondary alkyl halides.
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DOI: 10.1039/c7cc07122a
Abstract: A catalytic asymmetric alkylation of fully substituted enolates with racemic, non-activated secondary alkyl halides is described. The chiral 1,2,3-triazolium ion enables excellent diastereo- and enantiocontrol via enantiofacial discrimination of prochiral enolates and kinetic resolution of… read more here.
Keywords: alkyl halides; diastereo enantioselective; enantioselective phase; alkylation ... See more keywords
Asymmetric binary-acid catalysis: a diastereo- and enantioselective oxa-Nazarov cyclization-Michael addition of conjugated 1,2-diketones
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00558e
Abstract: Diastereo- and enantioselective oxa-Nazarov cyclization-Michael addition of conjugated 1,2-diketones was achieved by using an asymmetric binary-acid catalysis with chiral phosphoric acid and FeBr3. The reaction affords the corresponding chiral 3(2H)-furanones... read more here.
Keywords: nazarov cyclization; enantioselective oxa; diastereo enantioselective; oxa nazarov ... See more keywords