Regio- and Diastereoselective Access to Fused Isoxazolidines via Ru(II)-Catalyzed C-H Activation of Nitrones and Coupling with Perfluoroalkylolefins.
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DOI: 10.1021/acs.orglett.7b03775
Abstract: The synthsis of fluorinated isoxazolidines in bicyclic settings has been realized via Ru(II)-catalyzed C-H activation of aryl nitrones with perfluoroalkyl-substituted olefins as the coupling partner. The reaction proceeded via initial chelation-assisted C(aryl)-H allylation followed by… read more here.
Keywords: diastereoselective access; via catalyzed; regio diastereoselective; catalyzed activation ... See more keywords
Diastereoselective access to substituted oxetanes via hydrosilylation-iodocyclisation of homopropargylic alcohols.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03339a
Abstract: The regio and stereoselective hydrosilylation of a variety of homopropargylic alcohols and their derivatives is described. The reaction is tolerant to a variety of sterically and electronically varied substrates, affording only the E-vinyl silane as… read more here.
Keywords: substituted oxetanes; diastereoselective access; access substituted; homopropargylic alcohols ... See more keywords