Asymmetric Hydrogenation of Dibenzo[ c,e]azepine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01859
Abstract: An efficient Ru-catalyzed asymmetric hydrogenation of dibenzo[ c, e]azepines is reported. A series of seven-membered cyclic amines were obtained with moderate to excellent enantioselectivity. The catalyst counteranion played an important role in achieving high-level chiral… read more here.
Keywords: azepine derivatives; dibenzo azepine; asymmetric hydrogenation; hydrogenation dibenzo ... See more keywords
Strategies in the synthesis of dibenzo[b,f]heteropines
Sign Up to like & getrecommendations! Published in 2023 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.19.51
Abstract: The dibenzo[b,f]azepine skeleton is important in the pharmaceutical industry, not only in terms of existing commercial antidepressants, anxiolytics and anticonvulsants, but also in reengineering for other applications. More recently, the potential of the dibenzo[b,f]azepine moiety… read more here.
Keywords: strategies synthesis; synthesis dibenzo; chemistry; dibenzo heteropines ... See more keywords