Dibenzocyclooctendiones (DBCDOs): Arginine-Selective Chemical Labeling Reagents Obtained through Benzilic Acid Rearrangement.
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DOI: 10.1021/acs.orglett.2c01970
Abstract: We demonstrate that dibenzocyclooctendiones (DBCDOs) are efficient chemical reagents for the site-specific labeling of arginine-containing biomolecules. Unlike the commonly used probes, DBCDOs undergo an irreversible ring-contracted rearrangement with the guanidinium group on arginine residues under… read more here.
Keywords: selective chemical; arginine selective; dbcdos arginine; dibenzocyclooctendiones dbcdos ... See more keywords