Dicer dependent tRNA derived small RNAs promote nascent RNA silencing
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DOI: 10.1093/nar/gkac022
Abstract: Abstract In mammalian cells, small non-coding RNAs (sncRNAs) negatively regulate gene expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into post-transcriptional gene silencing (PTGS), which involves the cleavage of target… read more here.
Keywords: nascent rna; small rnas; trna derived; gene ... See more keywords
Expression of Concern on ‘DICER-dependent biogenesis of let-7 miRNAs affects human cell response to DNA damage via targeting p21/p27’
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DOI: 10.1093/nar/gkac553
Abstract: When similar allegations were brought to the Editors’ attention again in late 2021, the journal re-opened the investigation. With newer techniques, the journal also identified potential concerns with Figure 2D. While the corresponding author works… read more here.
Keywords: expression concern; concern dicer; dependent biogenesis; let mirnas ... See more keywords