1,3‐Dichloro‐2‐propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes
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DOI: 10.1002/tox.23615
Abstract: 1,3‐Dichloro‐2‐propanol (1,3‐DCP) is a representative chloropropane environmental contaminant with multiple toxicities. Ferroptosis is a novel iron‐dependent form of regulated cell death that is closely associated with the accumulation of lipid peroxides, Fe2+ and reactive oxygen… read more here.
Keywords: signaling pathway; nrf2 signaling; dichloro propanol; induced ferroptosis ... See more keywords
Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway
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DOI: 10.1016/j.lfs.2017.12.040
Abstract: &NA; Accumulating evidence reveals the association of 1, 3‐dichloro‐2‐propanol (1, 3‐DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti‐inflammatory activities. Here, we showed… read more here.
Keywords: lipogenesis; hepg2 cells; dichloro propanol; activation ... See more keywords