1,3‐Dichloro‐2‐propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes
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DOI: 10.1002/tox.23615
Abstract: 1,3‐Dichloro‐2‐propanol (1,3‐DCP) is a representative chloropropane environmental contaminant with multiple toxicities. Ferroptosis is a novel iron‐dependent form of regulated cell death that is closely associated with the accumulation of lipid peroxides, Fe2+ and reactive oxygen… read more here.
Keywords: signaling pathway; nrf2 signaling; dichloro propanol; induced ferroptosis ... See more keywords
Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.12.040
Abstract: &NA; Accumulating evidence reveals the association of 1, 3‐dichloro‐2‐propanol (1, 3‐DCP) exposure and lipogenesis. Alliin, the most abundant sulphur compound in garlic, has been demonstrated to exhibit hypoglycemic, antioxidant and anti‐inflammatory activities. Here, we showed… read more here.
Keywords: lipogenesis; hepg2 cells; dichloro propanol; activation ... See more keywords
1,3-Dichloro-2-propanol Induced Renal Cell Ferroptosis via the Circadian Clock Protein BMAL1 Targeting GPX4.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c05676
Abstract: 1,3-Dichloro-2-propanol (1,3-DCP), a representative chloropropyl alcohol contaminant in food, has shown toxic effects on the kidney. Ferroptosis is a newly identified cell death driven by iron-dependent lipid peroxidation that is associated with renal injury. However,… read more here.
Keywords: dcp; dichloro propanol; ferroptosis; clock ... See more keywords