Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors.
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DOI: 10.1021/acsmedchemlett.4c00206
Abstract: In this study, a focused library of oxime ester derivatives of 2,4-dichloro-5-sulfamoylbenzoic acid (lasamide) containing Schiff bases was synthesized and tested in vitro for their ability to inhibit the cytosolic human carbonic anhydrases (hCAs) I… read more here.
Keywords: sulfamoylbenzoic acid; dichloro sulfamoylbenzoic; oxime esters; human carbonic ... See more keywords