Articles with "dichloroacetic acid" as a keyword



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Degradation of dichloroacetic acid in a novel corona discharge reactor integrated with microbubbles generation

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Published in 2021 at "Separation and Purification Technology"

DOI: 10.1016/j.seppur.2021.119019

Abstract: Abstract The development of feasible and environmentally friendly technologies to remove dichloroacetic acid (DCAA) from water is needed worldwide to reduce human exposure to this common disinfection byproduct and to minimize cancer risk. In this… read more here.

Keywords: dichloroacetic acid; discharge reactor; corona discharge; degradation ... See more keywords
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Metabolic reprogramming by Dichloroacetic acid potentiates photodynamic therapy of human breast adenocarcinoma MCF-7 cells

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Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0206182

Abstract: Aberrant glycolytic metabolism is one of the hallmarks of carcinogenesis and therefore reversal of metabolic transformation is a promising drug target in cancer treatment strategies. Dichloroacetic acid (DCA) is known to target the glycolytic pathway… read more here.

Keywords: therapy; mcf cells; dichloroacetic acid; photodynamic therapy ... See more keywords
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Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s194329

Abstract: Background Metabolic reprogramming is a characteristic of tumor cells and is considered a potential therapeutic target. Even under aerobic conditions, tumor cells use glycolysis to produce energy, a phenomenon called the “Warburg effect”. Pyruvate dehydrogenase… read more here.

Keywords: expression; dichloroacetic acid; metabolism; production ... See more keywords