Effect of probiotic supplementation on oxidative stress markers in rats with diclofenac-induced hepatotoxicity
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Microbiology"
DOI: 10.1007/s42770-020-00302-4
Abstract: In this study, we have investigated the effect of an antioxidant probiotic pretreatment toward an overdose of diclofenac in rats (100 mg/kg bw). Rats were treated daily with the probiotic Streptococcus salivarius St.sa (10 9 CFU) during… read more here.
Keywords: induced hepatotoxicity; diclofenac induced; effect; hepatotoxicity ... See more keywords
Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF‐&kgr;B activity
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.07.038
Abstract: Aims: Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely used and effective anti‐inflammatories despite the well‐known side effects such as gastrointestinal damage, acute kidney injury (AKI), and cardiovascular dysfunctions. Diclofenac is among the most prescribed NSAIDs due… read more here.
Keywords: pdtc; diclofenac induced; acute kidney; damage ... See more keywords
Naringin and Hesperidin Counteract Diclofenac-Induced Hepatotoxicity in Male Wistar Rats via Their Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities
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DOI: 10.1155/2021/9990091
Abstract: This study is aimed at evaluating the preventive effect and at suggesting the mode of actions of naringin and hesperidin and their combination in diclofenac-induced hepatotoxicity. Male Wistar rats, intraperitoneally injected with diclofenac sodium (3 mg/kg… read more here.
Keywords: induced hepatotoxicity; hepatotoxicity male; diclofenac induced; diclofenac ... See more keywords