Selective Zincation of 1,2-Dicyanobenzene and Related Benzonitriles in Continuous Flow Using In Situ Trapping Metalations
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DOI: 10.1055/s-0036-1588837
Abstract: A mild and general metalation procedure for the functionalization of 1,2-dicyanobenzene and related polyfunctionalized benzonitriles using a commercially available continuous flow setup is reported. The addition of TMPLi (TMP = 2,2,6,6-tetramethylpiperidyl) to a mixture of… read more here.
Keywords: situ trapping; dicyanobenzene related; continuous flow; trapping metalations ... See more keywords