Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)
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DOI: 10.3762/bjoc.18.153
Abstract: The chemical synthesis of the dideuterium-labelled ATP analogue 1-adenosin-5’-yl-3-(3-methylbut-3-en-1,1-d2-1-ol) triphosphoric acid diester (ApppI(d2)) is described. ApppI has been reported to be an important mevalonate pathway metabolite, induced by nitrogen-containing bisphosphonates used for the treatment of… read more here.
Keywords: synthesis biologically; synthesis; dideuterium labelled; biologically important ... See more keywords