Chemopreventive effect of dieckol against 7,12‐dimethylbenz(a)anthracene induced skin carcinogenesis model by modulatory influence on biochemical and antioxidant biomarkers
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Toxicology"
DOI: 10.1002/tox.23082
Abstract: Skin cancer is the commonly found type, which contributes to 40% of whole cancer incidences worldwide. Dieckol is an active compound occurs in the marine algae with many biological benefits. In this exploration, we intended… read more here.
Keywords: skin carcinogenesis; dieckol dimethylbenz; dieckol; dimethylbenz anthracene ... See more keywords
Highly Regioselective Preparation and Characterization of New 6-O-Substituted Dieckol Derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2020.08.012
Abstract: Abstract Dieckol is a brown algae-derived polyphenol that has broad bioactivity and low toxicity. Therefore, it is a promising lead compound for the development of therapeutic agents to treat various pathological conditions, including viral infections,… read more here.
Keywords: dieckol; dieckol derivatives; hydroxyl groups; preparation characterization ... See more keywords
Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9040438
Abstract: Nitric oxide (NO), an endothelial-derived relaxing factor synthesized by endothelial nitric oxide synthase (eNOS) in endothelial cells, enhances vasodilation by modulating vascular tone. The calcium concentration critically influences eNOS activation in endothelial cells. Thus, modulation… read more here.
Keywords: vasodilation; dieckol; ecklonia cava; pi3k akt ... See more keywords
Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model
Sign Up to like & getrecommendations! Published in 2021 at "Marine Drugs"
DOI: 10.3390/md19080443
Abstract: One of the well-known causes of hearing loss is noise. Approximately 31.1% of Americans between the ages of 20 and 69 years (61.1 million people) have high-frequency hearing loss associated with noise exposure. In addition,… read more here.
Keywords: hearing loss; pff; dieckol; noise ... See more keywords
Regioselective Synthesis of 6-O-Acetyl Dieckol and Its Selective Cytotoxicity against Non-Small-Cell Lung Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20110683
Abstract: Dieckol, a phlorotannin from Ecklonia cava, has shown potential for use as an anticancer agent that selectively kills cancer cells. However, it is necessary to amplify its potency without damaging its inherent safety in order… read more here.
Keywords: dieckol; cytotoxicity; cancer cells; regioselective synthesis ... See more keywords