Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM
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DOI: 10.1038/s41598-020-67513-5
Abstract: Single-nucleus RNA sequencing (snRNA-seq) measures gene expression in individual nuclei instead of cells, allowing for unbiased cell type characterization in solid tissues. We observe that snRNA-seq is commonly subject to contamination by high amounts of… read more here.
Keywords: seq; single nucleus; diem; rna ... See more keywords