Cascade Radical 1,6-Addition/Cyclization of para-Quinone Methides: Leading to Spiro[4.5]deca-6,9-dien-8-ones.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00518
Abstract: A cascade three-component iodoazidation of para-quinone methides to construct spiro[4.5]deca-6,9-dien-8-ones under mild conditions has been developed. The chemoselective 1,6-addition of azide radical triggered a regioselective 5-exo-dig cyclization/radical coupling sequence, enabling C-N, C-C, and C-I bond… read more here.
Keywords: spiro deca; quinone methides; dien ones; para quinone ... See more keywords
Selective syntheses of diversely substituted 2-hydroxy-4′-hydroxybenzophenones through [4 + 2] or [3 + 3] annulation of penta-3,4-dien-2-ones with 3-formylchromones
Sign Up to like & getrecommendations! Published in 2017 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo00366h
Abstract: A selective synthesis of 2-hydroxy-4′-hydroxybenzophenones or their 3′-acylated counterparts through the cascade reactions of 3-formylchromones with diversely substituted penta-3,4-dien-2-ones is presented. Mechanistically, the formation of the title compounds involves either an unprecedented [4 + 2]… read more here.
Keywords: annulation; hydroxy hydroxybenzophenones; dien ones; selective syntheses ... See more keywords
Novel Asymmetric Thiazolyl-Substituted Penta-1,4-Dien-3-Ones and 3,5-Diaryl-2-Pyrazolines
Sign Up to like & getrecommendations! Published in 2020 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2020.1858882
Abstract: Various diaryl/hetaryl representatives of penta-1,4-dien-3-one series attract the attention of synthetic chemists during several decades owing to the possibility of their consequent chemical modifi... read more here.
Keywords: substituted penta; asymmetric thiazolyl; novel asymmetric; dien ones ... See more keywords
Reactions of phosphorylated 2,6-di-tert-butyl-4-methylidenecyclohexa-2,5-dien-1-ones with aliphatic, aromatic, and heteroaromatic thiols
Sign Up to like & getrecommendations! Published in 2017 at "Russian Journal of General Chemistry"
DOI: 10.1134/s107036321705036x
Abstract: The addition of alkanethiols, benzenethiol, and hetarenethiols to phosphorylated quinomethanes afforded P,S- and N,P,S-containing polyfunctional organic compounds as potential bactericidal agents. read more here.
Keywords: phosphorylated tert; methylidenecyclohexa dien; dien ones; reactions phosphorylated ... See more keywords
Dearomatization of 3-Aminophenols for Synthesis of Spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones via Hydride Transfer Strategy-Enabled [5+1] Annulations
Sign Up to like & getrecommendations! Published in 2024 at "Molecules"
DOI: 10.3390/molecules29051012
Abstract: The Sc(OTf)3-catalyzed dearomative [5+1] annulations between readily available 3-aminophenols and O-alkyl ortho-oxybenzaldehydes were developed for synthesis of spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones. The “two-birds-with-one-stone” strategy was disclosed by the dearomatization of phenols and direct α-C(sp3)–H bond functionalization of oxygen… read more here.
Keywords: spiro chromane; dien ones; chromane cyclohexane; hydride transfer ... See more keywords