Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats
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DOI: 10.3390/nu12092634
Abstract: Introduction: FOLFOX chemotherapy (CTx) is used for the treatment of colorectal liver metastasis (CRLM). Side effects include rare cardiotoxicity, which may limit the application of FOLFOX. Currently, there is no effective strategy to prevent FOLFOX-induced… read more here.
Keywords: heart; dietary glycine; treatment; folfox ... See more keywords
Dietary glycine decreases both tumor volume and vascularization in a combined colorectal liver metastasis and chemotherapy model
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.35513
Abstract: Rationale: Chemotherapy (CTx) with FOLFOX is indicated prior to resection of liver metastases; however, its effect is limited due to chemoresistance and its toxicity prevents from aggressive surgery needed in some cases. Hepatoprotective glycine has… read more here.
Keywords: dietary glycine; tumor volume; colorectal liver; glycine ... See more keywords