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Published in 2018 at "Biological Trace Element Research"
DOI: 10.1007/s12011-018-1446-3
Abstract: Imbalance of iron homeostasis has been involved in clinical courses of metabolic diseases such as type 2 diabetes mellitus, obesity, and nonalcoholic fatty liver, through mechanisms not yet fully elucidated. Herein, we evaluated the effect…
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Keywords:
homeostasis;
dietary iron;
iron modulates;
modulates glucose ... See more keywords
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Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.07.016
Abstract: Pathogen virulence exists on a continuum. The strategies that drive symptomatic or asymptomatic infections remain largely unknown. We took advantage of the concept of lethal dose 50 (LD50) to ask which component of individual non-genetic variation…
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Keywords:
dietary iron;
pathogen;
cooperative metabolic;
virulence ... See more keywords
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Published in 2019 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2019.02.012
Abstract: BACKGROUND & AIMS Type I hereditary hemochromatosis (HH) and dysmetabolic iron overload syndrome (DIOS) are the two most prevalent iron overload diseases. Although many food components, particularly polyphenols, reduce iron bioavailability, there is no clinically…
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Keywords:
iron;
iron absorption;
dietary iron;
iron overload ... See more keywords
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Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.114159
Abstract: The present study investigated the effects of dietary iron (Fe) exposure on physiological performance and homeostatic regulation of trace metals during development (5-28 days post-fertilization; dpf) in zebrafish (Danio rerio). The results demonstrated that whole…
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Keywords:
dietary iron;
iron exposure;
exposure;
metal ... See more keywords
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Published in 2021 at "Journal of the Academy of Nutrition and Dietetics"
DOI: 10.1016/j.jand.2021.07.005
Abstract: BACKGROUND A food frequency questionnaire (FFQ) for South American children and adolescents was developed, but its validity for assessing dietary iron intake has not been evaluated. OBJECTIVE To evaluate the validity of the FFQ and…
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Keywords:
dietary iron;
intake;
iron intake;
south american ... See more keywords
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Published in 2018 at "European Journal of Clinical Nutrition"
DOI: 10.1038/s41430-018-0221-z
Abstract: A healthy adult requires about 25–30 mg iron per day for synthesis of red blood cells and iron-containing enzymes. Most of this iron requirement (20–25 mg) is needed to synthesize hemoglobin for the daily production…
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Keywords:
absorption;
supply;
dietary iron;
tissue ... See more keywords
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Published in 2017 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2017.1395935
Abstract: ABSTRACT Transfusion-independent patients with thalassemia intermedia (TI) develop fatal iron overload from excessive iron absorption triggered by ineffective erythropoiesis. More information about iron pharmacokinetics and nonheme, dietary iron absorption in such patients is needed to…
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Keywords:
iron;
ferrous sulfate;
ferritin ferrous;
dietary iron ... See more keywords
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Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz044.p24-057-19
Abstract: Objectives Although iron fortification/supplementation is recommended for infants (6 to 12 months) and toddlers by pediatrics, the optimal dose is still largely debated. One of controversies centers on whether iron fortification at recommended dose increases…
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Keywords:
dietary iron;
infection;
enterotoxigenic coli;
piglet model ... See more keywords
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Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz048.fs04-01-19
Abstract: Objectives In the US, prophylactic iron supplementation without thorough screening for iron deficiency is commonly practiced in both normal weight and low birth weight infants. In a nursing pig model, we previously found that excess…
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Keywords:
expression;
dietary iron;
high iron;
birth weight ... See more keywords
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Published in 2023 at "Blood"
DOI: 10.1182/blood.2022016632
Abstract: Iron is an essential cellular metal that is important for many physiological functions including erythropoiesis and host defense. It is absorbed from the diet in the duodenum and loaded onto transferrin, the main iron transport…
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Keywords:
dietary iron;
transferrin;
iron;
local degradation ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202460
Abstract: Inflammatory bowel disease (IBD) is associated with anaemia and oral iron replacement to correct this can be problematic, intensifying inflammation and tissue damage. The intestinal microbiota also plays a key role in the pathogenesis of…
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Keywords:
dietary iron;
colitis;
400 ppm;
iron ... See more keywords