Do differences in cell lines and methods used for calculation of IC50 values influence categorisation of drugs as P-glycoprotein substrates and inhibitors?
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2135040
Abstract: Abstract In vitro bidirectional assays are employed to determine whether a drug is a substrate and/or inhibitor of P-glycoprotein (P-gp) transport. Differences between cell lines and calculation methods can lead to variations in the determination… read more here.
Keywords: calculation methods; differences cell; cell lines; ic50 values ... See more keywords
Regional differences in cell‐mediated immunity in people with diabetic peripheral neuropathy
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DOI: 10.1111/dme.14143
Abstract: To study cell‐mediated immunity in the feet of people with type 2 diabetes with polyneuropathy. read more here.
Keywords: cell mediated; people diabetic; immunity people; differences cell ... See more keywords