Differences in set-based tests for sparse alternatives when testing sets of outcomes compared to sets of explanatory factors in genetic association studies.
Sign Up to like & getrecommendations! Published in 2022 at "Biostatistics"
DOI: 10.1093/biostatistics/kxac036
Abstract: Set-based association tests are widely popular in genetic association settings for their ability to aggregate weak signals and reduce multiple testing burdens. In particular, a class of set-based tests including the Higher Criticism, Berk-Jones, and… read more here.
Keywords: differences set; set based; explanatory factors; based tests ... See more keywords