EFhd2 brain interactome reveals its association with different cellular and molecular processes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neurochemistry"
DOI: 10.1111/jnc.15517
Abstract: EFhd2 is a conserved calcium-binding protein that is highly expressed in the central nervous system. We have shown that EFhd2 interacts with tau protein, a key pathological hallmark in Alzheimer's disease and related dementias. However,… read more here.
Keywords: efhd2 brain; cellular molecular; molecular processes; brain ... See more keywords
Abstract 549: Characterization of the selective inhibitory effect of KRas inhibitors in different cellular assay formats
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-549
Abstract: The proto-oncogene KRas is a well-described small GTPase that functions as a molecular switch for major physiological signaling pathways involved in cell proliferation, differentiation and survival. It has been shown that activating mutations in KRas… read more here.
Keywords: selective inhibitory; different cellular; inhibitory effect; effect ... See more keywords
Moonlighting Activity of Secreted Inflammation-Regulatory Proteins
Sign Up to like & getrecommendations! Published in 2018 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2018.59.4.463
Abstract: Moonlighting proteins exhibit multiple activities in different cellular compartments, and their abnormal regulation could play an important role in many diseases. To date, many proteins have been identified with moonlighting activity, and more such proteins… read more here.
Keywords: moonlighting activity; exhibit multiple; inflammation; proteins exhibit ... See more keywords