Scouting in silico different chemo-types of PDE4 inhibitors to guide the design of new anti-inflammatory/antioxidant agents.
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DOI: 10.1002/cmdc.202300046
Abstract: During the last years, we developed a large library of new selective phosphodiesterase 4D inhibitors, maintaining the catechol portion of the well-known PDE4 inhibitor Rolipram, featuring different substitutions in place of the lactam group of… read more here.
Keywords: pde4 inhibitors; scouting silico; anti inflammatory; silico different ... See more keywords