A semi-supervised ensemble clustering algorithm for discovering relationships between different diseases by extracting cell-to-cell biological communications
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-023-05559-4
Abstract: Introduction In recent decades, many theories have been proposed about the cause of hereditary diseases such as cancer. However, most studies state genetic and environmental factors as the most important parameters. It has been shown… read more here.
Keywords: cell cell; different diseases; relationships different; cell ... See more keywords
Exploring AT2R and its polymorphism in different diseases: An approach to develop AT2R as a drug target beyond hypertension.
Sign Up to like & getrecommendations! Published in 2021 at "Current drug targets"
DOI: 10.2174/1389450122666210806125919
Abstract: The Angiotensin II type 2 receptor (AT2R) is one of the critical components of the renin-angiotensin system (RAS), which performs diverse functions like inhibiting cell differentiation, cell proliferation, vasodilatation, reduces oxidative stress and inflammation. AT2R… read more here.
Keywords: at2r drug; drug; drug target; different diseases ... See more keywords
Comparative Transcriptional Analysis of Pulmonary Arterial Hypertension Associated With Three Different Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.672159
Abstract: Pulmonary arterial hypertension (PAH) is a severe cardiovascular disorder with high mortality. Multiple clinical diseases can induce PAH, but the underlying molecular mechanisms shared in PAHs associated with different diseases remain unclear. The aim of… read more here.
Keywords: associated three; arterial hypertension; analysis; pulmonary arterial ... See more keywords
Gut Microbiota: The Potential Key Target of TCM’s Therapeutic Effect of Treating Different Diseases Using the Same Method—UC and T2DM as Examples
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.855075
Abstract: Traditional Chinese herbal medicine often exerts the therapeutic effect of “treating different diseases with the same method” in clinical practice; in other words, it is a kind of herbal medicine that can often treat two… read more here.
Keywords: medicine; different diseases; treating different; effect treating ... See more keywords
IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1533335
Abstract: Interleukin-33 (IL-33) is a nuclear factor and member of the IL-1 cytokine family. IL-33 is mainly expressed by epithelial and endothelial cells and exerts its function through interaction with various immune cells, and binding to… read more here.
Keywords: role; st2 signaling; different diseases; st2 ... See more keywords
Health-Related Quality of Life in Patients With Different Diseases Measured With the EQ-5D-5L: A Systematic Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2021.675523
Abstract: Background: The EQ-5D-5L is a generic preference-based questionnaire developed by the EuroQol Group to measure health-related quality of life (HRQoL) in 2005. Since its development, it has been increasingly applied in populations with various diseases… read more here.
Keywords: patients different; health; rem fem; different diseases ... See more keywords
Biogenesis, Biologic Function and Clinical Potential of Exosomes in Different Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10134428
Abstract: Exosomes are extracellular vesicles (EVs) belonging to the nanovesicles family that function as signaling molecules between cells. After their first description in the late 1960s, interest in their potential as a research target has steadily… read more here.
Keywords: exosomes different; biogenesis biologic; biologic function; different diseases ... See more keywords
A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710014
Abstract: Histone deacetylases (HDACs) are epigenetic enzymes which participate in transcriptional repression and chromatin condensation mechanisms by removing the acetyl moiety from acetylated ε-amino group of histone lysines and other non-histone proteins. In recent years, HDAC8,… read more here.
Keywords: hdac8; perspective hdac8; diseases overview; different diseases ... See more keywords
Emerging Roles of NDUFS8 Located in Mitochondrial Complex I in Different Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248754
Abstract: NADH:ubiquinone oxidoreductase core subunit S8 (NDUFS8) is an essential core subunit and component of the iron-sulfur (FeS) fragment of mitochondrial complex I directly involved in the electron transfer process and energy metabolism. Pathogenic variants of… read more here.
Keywords: mitochondrial complex; different diseases; emerging roles; diabetes mellitus ... See more keywords
Same Fragments, Different Diseases: Analysis of Identical tRNA Fragments Across Diseases Utilizing Functional and Abundance-Based Databases
Sign Up to like & getrecommendations! Published in 2025 at "Non-Coding RNA"
DOI: 10.3390/ncrna11050063
Abstract: Background/Objectives: Transfer RNA-derived fragments (tRFs) are small non-coding RNAs increasingly implicated in gene regulation and disease, yet their target specificity and disease relevance remain poorly understood. This is an exploratory study that investigates the phenomenon… read more here.
Keywords: abundance; disease; abundance based; fragments different ... See more keywords
Trackins (Trk-Targeting Drugs): A Novel Therapy for Different Diseases
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceuticals"
DOI: 10.3390/ph17070961
Abstract: Many routes may lead to the transition from a healthy to a diseased phenotype. However, there are not so many routes to travel in the opposite direction; that is, therapy for different diseases. The following… read more here.
Keywords: trackins trk; targeting drugs; different diseases; therapy different ... See more keywords