Different mutations in SARS-CoV-2 associate with severe and mild outcome
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DOI: 10.1016/j.ijantimicag.2020.106272
Abstract: Introduction Genomic alterations in a viral genome can lead to either better or worse outcome and identifying these mutations is of utmost importance. Here, we correlated protein-level mutations in the SARS-CoV-2 virus to clinical outcome.… read more here.
Keywords: outcome; mutations sars; mild outcome; cov associate ... See more keywords
Different Mutations of Gap Junction Connexin 47 Lead to Discrepant Activation of Unfolded Protein Response Pathway in Pelizaeus‐Merzbacher‐Like Disease
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DOI: 10.1055/s-0037-1603978
Abstract: Background The unfolded protein response (UPR) includes three cascade pathways, which are responsible for the elimination of overload protein that is accumulated in the endoplasmic reticulum (ER). We hypothesize that mutations in connexin 47 (Cx47)… read more here.
Keywords: pelizaeus merzbacher; unfolded protein; protein response; merzbacher like ... See more keywords