Chemical Synthesis of Cys-Containing Protein via Chemoselective Deprotection with Different Palladium Complexes.
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DOI: 10.1021/acs.orglett.9b03152
Abstract: We report selective removals of N-terminal and internal Cys protecting groups using different palladium complexes to facilitate the efficient chemical protein synthesis. Utilizing the orthogonal deprotection pairs, we accomplished chemical synthesis of histone H3 containing… read more here.
Keywords: different palladium; palladium complexes; cys; deprotection ... See more keywords