The effect on ion channel of different protonation states of E90 in channelrhodopsin-2: a molecular dynamics simulation
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DOI: 10.1039/d1ra01879e
Abstract: With E90 protonated, the proton acceptor of RSBH+ is E123 with a narrow channel along TM3; while with E90 deprotonated, proton transfer from RSBH+ to D253 generates an approximately open channel along TM2. read more here.
Keywords: channel; different protonation; protonation states; ion channel ... See more keywords