Articles with "different unbinding" as a keyword



Agonists and Antagonists Show Different Unbinding Paths from the TLR8 Receptor

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Published in 2025 at "Journal of Chemical Information and Modeling"

DOI: 10.1021/acs.jcim.5c00496

Abstract: Toll-like receptors (TLRs) form the first barrier of the innate immune system. TLR8 is an important target to treat autoimmune diseases since its ligand-induced degree of activation regulates immune response and associated hyperinflammation. Molecular dynamics… read more here.

Keywords: receptor; antagonists show; different unbinding; show different ... See more keywords