Articles with "differential activity" as a keyword



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Differential activity of APOBEC3F, APOBEC3G, and APOBEC3H in the restriction of HIV-2.

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Published in 2021 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2021.167355

Abstract: Human immunodeficiency virus (HIV) mutagenesis is driven by a variety of internal and external sources, including the host APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypetide-like 3; A3) family of restriction factors, which catalyze G-to-A… read more here.

Keywords: restriction; restriction hiv; hiv; differential activity ... See more keywords
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Differential Activity of Transcribed Enhancers in the Prefrontal Cortex of 537 cases with Schizophrenia and Controls

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Published in 2018 at "Molecular psychiatry"

DOI: 10.1038/s41380-018-0059-8

Abstract: Transcription at enhancers is a widespread phenomenon which produces so-called enhancer RNA (eRNA) and occurs in an activity-dependent manner. However, the role of eRNA and its utility in exploring disease-associated changes in enhancer function, and… read more here.

Keywords: transcribed enhancers; schizophrenia; activity transcribed; expression ... See more keywords
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Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1

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Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0254466

Abstract: Relaxin/insulin-like family peptide receptor 1 (RXFP1) mediates relaxin’s antifibrotic effects and has reduced expression in the lung and skin of patients with fibrotic interstitial lung disease (fILD) including idiopathic pulmonary fibrosis (IPF) and systemic sclerosis… read more here.

Keywords: lung; activity fibrotic; rxfp1; differential activity ... See more keywords