Differential gene expression analysis of RAGE‐S100A6 complex for target selection and the design of novel inhibitors for anticancer drug discovery
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30356
Abstract: Receptor for advanced glycation end products (RAGE), a member of the immunoglobulin family, interactions with its ligands trigger downstream signaling and induce an inflammatory response linked to diabetes, inflammation, carcinogenesis, cardiovascular disease, and a variety… read more here.
Keywords: rage; rage s100a6; s100a6 complex; differential gene ... See more keywords
Identification and validation of reference genes for reliable analysis of differential gene expression during antibiotic induced persister formation in Klebsiella pneumoniae using qPCR.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2021.106165
Abstract: The study of differential gene expression in persister cells is compounded by ceasure of conventional cellular metabolic pathways during persistence. There is, hence, a requirement to identify and validate suitable reference genes whose expression remains… read more here.
Keywords: differential gene; persister; gene expression; formation ... See more keywords
Differential gene expression in Drosophilamelanogaster and D.nigrosparsa infected with the same Wolbachia strain
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90857-5
Abstract: Wolbachia are maternally inherited endosymbionts that infect nearly half of all arthropod species. Wolbachia manipulate their hosts to maximize their transmission, but they can also provide benefits such as nutrients and resistance against viruses to… read more here.
Keywords: differential gene; wolbachia strain; expression; gene expression ... See more keywords
Analysis of Differential Gene Expression of the Aquatic Insect Protohermes costalis (Walker) (Megaloptera: Corydalidae) in Response to Cadmium Exposure
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Entomology"
DOI: 10.1093/ee/nvac041
Abstract: Abstract Heavy metal pollution in freshwater ecosystems is a serious threat to aquatic organisms. Species of Megaloptera are important predators of aquatic invertebrates and have been widely used as bioindicators in assessing the quality of… read more here.
Keywords: expression; analysis; gene expression; differential gene ... See more keywords
A Composite Mode Differential Gene Regulatory Architecture based on Temporal Expression Profiles
Sign Up to like & getrecommendations! Published in 2019 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2018.2828418
Abstract: Exploring the complex interactive mechanism in a Gene Regulatory Network (GRN) developed using transcriptome data obtained from standard microarray and/or RNA-seq experiments helps us to understand the triggering factors in cancer research. The Transcription Factor… read more here.
Keywords: regulatory architecture; differential gene; gene; gene regulatory ... See more keywords
Differential Gene expression related to morphological variation in the adductor muscle tissues of diploid and triploid fujian oysters, Crassostrea angulata
Sign Up to like & getrecommendations! Published in 2019 at "Aquaculture Research"
DOI: 10.1111/are.14312
Abstract: The Fujian oyster, Crassostrea angulata, accounts for approximately 50% of the total oyster production in China and is one of the most economically important marine products. In this study, we investigated differential gene expression profiles… read more here.
Keywords: diploid triploid; differential gene; crassostrea angulata; gene expression ... See more keywords
Comparative analysis of differential gene expression analysis tools for single-cell RNA sequencing data
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2599-6
Abstract: BackgroundThe analysis of single-cell RNA sequencing (scRNAseq) data plays an important role in understanding the intrinsic and extrinsic cellular processes in biological and biomedical research. One significant effort in this area is the detection of… read more here.
Keywords: differential gene; analysis; gene expression; expression analysis ... See more keywords
Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network
Sign Up to like & getrecommendations! Published in 2020 at "BMC Bioinformatics"
DOI: 10.1186/s12859-020-03753-6
Abstract: Background Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, therefore characterizing the interconnectivity of genes is essential to unravel the underlying biological networks. However, the focus of… read more here.
Keywords: causal network; network; differential gene; regulatory pattern ... See more keywords
Differential gene expression analysis identified determinants of cell fate plasticity during radiation-induced regeneration in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009989
Abstract: Ionizing radiation (IR) is used to treat half of all cancer patients because of its ability to kill cells. IR, however, can induce stem cell-like properties in non-stem cancer cells, potentiating tumor regrowth and reduced… read more here.
Keywords: cell fate; fate plasticity; radiation; differential gene ... See more keywords
No pre-zygotic isolation mechanisms between Schistosoma haematobium and Schistosoma bovis parasites: From mating interactions to differential gene expression
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0009363
Abstract: Species usually develop reproductive isolation mechanisms allowing them to avoid interbreeding. These preventive barriers can act before reproduction, “pre-zygotic barriers”, or after reproduction, “post-zygotic barriers”. Pre-zygotic barriers prevent unfavourable mating, while post-zygotic barriers determine the… read more here.
Keywords: isolation mechanisms; zygotic barriers; differential gene; schistosoma haematobium ... See more keywords
Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182765
Abstract: Neuropathological studies often use autopsy brain tissue as controls to evaluate changes in protein or RNA levels in several diseases. In mesial temporal lobe epilepsy (MTLE), several genes are up or down regulated throughout the… read more here.
Keywords: differential gene; group; gene expression; expression ... See more keywords