Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117514
Abstract: AIMS Pigs are increasingly used as human metabolic disease models; however, there is insufficient research on breed-related genetic background differences. This study aimed to investigate the differential metabolic responses to high-fat and high-cholesterol (HFC) diet-induced… read more here.
Keywords: pig breeds; differential metabolic; cholesterol; two miniature ... See more keywords
Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans
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DOI: 10.1126/sciadv.abm9120
Abstract: Cellular metabolism has been proposed to govern distinct γδ T cell effector functions, but the underlying molecular mechanisms remain unclear. We show that interleukin-17 (IL-17)–producing γδ T (γδT17) and interferon-γ (IFN-γ)–producing γδ T (γδT1) cells… read more here.
Keywords: differential metabolic; t17 effector; maf; transcription factor ... See more keywords
Constant-Moderate and High-Intensity Interval Training Induce Differential Metabolic Benefits on Insulin-Sensitive Tissues in High-Fat Fed Mice
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DOI: 10.2337/db18-746-p
Abstract: Obesity associates highly with metabolic disorders including insulin resistance. To determine if two exercise prescriptions exert differential metabolic benefits in insulin sensitive tissues, we compared isocaloric programs of constant-moderate endurance (END) and high intensity interval… read more here.
Keywords: insulin sensitive; differential metabolic; benefits insulin; metabolic benefits ... See more keywords
Metabolomic and Transcriptomic Profiling Identified Significant Genes in Thymic Epithelial Tumor
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DOI: 10.3390/metabo12060567
Abstract: Thymomas and thymic carcinomas are malignant thymic epithelial tumors (TETs) with poor outcomes if non-resectable. However, the tumorigenesis, especially the metabolic mechanisms involved, is poorly studied. Untargeted metabolomics analysis was utilized to screen for differential… read more here.
Keywords: differential metabolic; metabolic patterns; thymic epithelial; metabolic scores ... See more keywords