Serum Metabolite Profile By Targeted Lipomics Approach to Evaluate Drug Resistance and Prognosis in Myeloma Patients
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-207172
Abstract: ObjectiveMultiple Myeloma (MM) is a plasma cell tumor that is prone to occur in elderly people. Drug resistance and repeated recurrence are important factors affecting the survival of MM patients, but the mechanism is unclear.… read more here.
Keywords: treatment; resistance; laccer d18; drug resistance ... See more keywords
Urine metabolomics of rats with chronic atrophic gastritis
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0236203
Abstract: Background/aim To use liquid chromatography-mass spectrometry (LC-MS) to identify endogenous differential metabolites in the urine of rats with chronic atrophic gastritis (CAG). Materials and methods Methylnitronitrosoguanidine (MNNG) was used to produce a CAG model in… read more here.
Keywords: differential metabolites; urine metabolomics; rats chronic; chronic atrophic ... See more keywords
Metabonomic Analysis of Metabolites Produced by Escherichia coli in Patients With and Without Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s388034
Abstract: Aim To analyze the metabolites of the most common sepsis-related pathogen and their correlation with clinical indicators. Methods Information of bacterial-infection patients in Huzhou Central hospital was retrospectively investigated and analyzed. The most common pathogen… read more here.
Keywords: sepsis; metabolism; escherichia coli; analysis ... See more keywords
Association of Differential Metabolites With Small Intestinal Microflora and Maternal Outcomes in Subclinical Hypothyroidism During Pregnancy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.779659
Abstract: Objective To investigate the association of differential metabolites with small intestinal microflora and maternal outcomes in subclinical hypothyroidism (SCH) during pregnancy. Methods The plasma of pregnant women in the SCH group and control group was… read more here.
Keywords: small intestinal; group; metabolites small; pregnancy ... See more keywords
Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1104295
Abstract: Objective To compare the differences in salivary metabolites between caries-active and caries-free children in the mixed dentition, and explore their correlation with caries status. Methods The study involved 20 children (aged 8–9 years) in the… read more here.
Keywords: free children; caries free; ion mode; caries active ... See more keywords
Discovery of potential biomarkers for osteoporosis using LC/GC−MS metabolomic methods
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1332216
Abstract: Purpose For early diagnosis of osteoporosis (OP), plasma metabolomics of OP was studied by untargeted LC/GC−MS in a Chinese elderly population to find possible diagnostic biomarkers. Methods A total of 379 Chinese community-dwelling older adults… read more here.
Keywords: potential biomarkers; discovery potential; osteoporosis using; using metabolomic ... See more keywords
The change of plasma metabolic profile and gut microbiome dysbiosis in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.931431
Abstract: Objective Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, which is associated with progressive disability, systemic complications, and early death. But its etiology and pathogenesis are not fully understood. We aimed to investigate the… read more here.
Keywords: metabolism; profile gut; rheumatoid arthritis; plasma ... See more keywords
Non-targeted metabolomic analysis of non-volatile metabolites in a novel Chinese industrially fermented low-salt kohlrabi
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2024.1450789
Abstract: Low-temperature and low-salt fermented Chinese kohlrabi (LSCK) represents a novel approach to producing low-salt kohlrabi without the need for desalination during processing, as compared to traditional techniques. However, the profile of its non-volatile metabolites remains… read more here.
Keywords: non volatile; low salt; differential metabolites; volatile metabolites ... See more keywords
Serum Metabolomics Coupling With Clinical Laboratory Indicators Reveal Taxonomic Features of Leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.794042
Abstract: Metabolic abnormality has been considered to be the seventh characteristic in cancer cells. The potential prospect of using serum biomarkers metabolites to differentiate ALL from AML remains unclear. The purpose of our study is to… read more here.
Keywords: differential metabolites; laboratory indicators; different types; clinical laboratory ... See more keywords
Plasma Metabolomics Identifies the Dysregulated Metabolic Profile of Primary Immune Thrombocytopenia (ITP) Based on GC-MS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845275
Abstract: ITP is a common autoimmune bleeding disorder with elusive pathogenesis. Our study was implemented to profile the plasma metabolic alterations of patients diagnosed with ITP, aiming at exploring the potential novel biomarkers and partial mechanism… read more here.
Keywords: plasma metabolomics; itp patients; itp; metabolomics identifies ... See more keywords
Source-specific metabolic profiles and gene expression in areca nut cultivars from Hainan (China)
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2025.1624083
Abstract: Areca catechu L. are versatile plants whose fruits and seeds have great economic value. Although widely cultivated in Hainan Province, China, including native (HN) and introduced varieties from Taiwan (TW), Thailand (TG), and Vietnam (YN),… read more here.
Keywords: areca nut; source specific; metabolic profiles; differential metabolites ... See more keywords