Urine metabolomics of rats with chronic atrophic gastritis
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DOI: 10.1371/journal.pone.0236203
Abstract: Background/aim To use liquid chromatography-mass spectrometry (LC-MS) to identify endogenous differential metabolites in the urine of rats with chronic atrophic gastritis (CAG). Materials and methods Methylnitronitrosoguanidine (MNNG) was used to produce a CAG model in… read more here.
Keywords: differential metabolites; urine metabolomics; rats chronic; chronic atrophic ... See more keywords
Metabonomic Analysis of Metabolites Produced by Escherichia coli in Patients With and Without Sepsis
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DOI: 10.2147/idr.s388034
Abstract: Aim To analyze the metabolites of the most common sepsis-related pathogen and their correlation with clinical indicators. Methods Information of bacterial-infection patients in Huzhou Central hospital was retrospectively investigated and analyzed. The most common pathogen… read more here.
Keywords: sepsis; metabolism; escherichia coli; analysis ... See more keywords
Association of Differential Metabolites With Small Intestinal Microflora and Maternal Outcomes in Subclinical Hypothyroidism During Pregnancy
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DOI: 10.3389/fcimb.2021.779659
Abstract: Objective To investigate the association of differential metabolites with small intestinal microflora and maternal outcomes in subclinical hypothyroidism (SCH) during pregnancy. Methods The plasma of pregnant women in the SCH group and control group was… read more here.
Keywords: small intestinal; group; metabolites small; pregnancy ... See more keywords
Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition
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DOI: 10.3389/fcimb.2023.1104295
Abstract: Objective To compare the differences in salivary metabolites between caries-active and caries-free children in the mixed dentition, and explore their correlation with caries status. Methods The study involved 20 children (aged 8–9 years) in the… read more here.
Keywords: free children; caries free; ion mode; caries active ... See more keywords
The change of plasma metabolic profile and gut microbiome dysbiosis in patients with rheumatoid arthritis
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DOI: 10.3389/fmicb.2022.931431
Abstract: Objective Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, which is associated with progressive disability, systemic complications, and early death. But its etiology and pathogenesis are not fully understood. We aimed to investigate the… read more here.
Keywords: metabolism; profile gut; rheumatoid arthritis; plasma ... See more keywords
Serum Metabolomics Coupling With Clinical Laboratory Indicators Reveal Taxonomic Features of Leukemia
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DOI: 10.3389/fphar.2022.794042
Abstract: Metabolic abnormality has been considered to be the seventh characteristic in cancer cells. The potential prospect of using serum biomarkers metabolites to differentiate ALL from AML remains unclear. The purpose of our study is to… read more here.
Keywords: differential metabolites; laboratory indicators; different types; clinical laboratory ... See more keywords
Plasma Metabolomics Identifies the Dysregulated Metabolic Profile of Primary Immune Thrombocytopenia (ITP) Based on GC-MS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845275
Abstract: ITP is a common autoimmune bleeding disorder with elusive pathogenesis. Our study was implemented to profile the plasma metabolic alterations of patients diagnosed with ITP, aiming at exploring the potential novel biomarkers and partial mechanism… read more here.
Keywords: plasma metabolomics; itp patients; itp; metabolomics identifies ... See more keywords
Pre- and Post-treatment Levels of Plasma Metabolites in Patients With Bipolar Depression
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DOI: 10.3389/fpsyt.2021.747595
Abstract: Background: Bipolar disorder (BD) is a serious mental disease with complex clinical manifestations and high recurrence rate. The purpose of this study was to detect metabolites related to the diagnosis and efficacy evaluation of bipolar… read more here.
Keywords: plasma metabolites; weeks medication; differential metabolites; depression ... See more keywords
Metabonomics Analysis of Stem Extracts from Dalbergia sissoo
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DOI: 10.3390/molecules27061982
Abstract: Dalbergia sissoo is a woody plant with economic and medicinal value. As the pharmacological qualities and properties of the wood from this plant primarily depend on its extractives, in this study, the metabolomic analysis of… read more here.
Keywords: dalbergia sissoo; metabonomics analysis; analysis; analysis stem ... See more keywords