Articles with "differential mobility" as a keyword



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Stable compensation voltages in differential mobility spectra by separating neutral vapors from ions in sample flow

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Published in 2020 at "International Journal for Ion Mobility Spectrometry"

DOI: 10.1007/s12127-020-00257-0

Abstract: In small planar differential mobility spectrometers with ambient pressure ion sources, both ions and neutral vapors of sample commonly flow from the ion source directly into and through the analyzer region. Although simple and convenient… read more here.

Keywords: neutral vapors; ion; differential mobility; compensation voltages ... See more keywords
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Separating and probing tautomers of protonated nucleobases using differential mobility spectrometry

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Published in 2017 at "International Journal of Mass Spectrometry"

DOI: 10.1016/j.ijms.2017.08.008

Abstract: Abstract The protonated nucleobases (C + H)+, (T + H)+, (U + H)+, (A + H)+, and (G + H)+ are investigated in a combined experimental and computational study using differential mobility spectrometry (DMS), mass spectrometry, and electronic structure calculations. DMS is used to isolate… read more here.

Keywords: protonated nucleobases; spectrometry; differential mobility; mobility spectrometry ... See more keywords
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Infrared isomer-specific fragmentation for the identification of aminobutyric acid isomers separated by differential mobility spectrometry

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Published in 2019 at "International Journal of Mass Spectrometry"

DOI: 10.1016/j.ijms.2019.05.014

Abstract: Abstract Metabolomics strongly relies on liquid chromatography hyphenated to tandem mass spectrometry (LC-MS/MS) for the separation and identification of metabolites. Retention times and fragmentation mass spectra are used as identification parameters. A complementary approach is… read more here.

Keywords: spectrometry; differential mobility; isomer specific; mass ... See more keywords
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Quantifying protein aggregation kinetics using electrospray differential mobility analysis.

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Published in 2019 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2019.112845

Abstract: Protein aggregation is a critical concern in bioprocessing, where its presence can result in serious adverse interactions in clinical end-use applications. In this study, an aerosol-based technique, electrospray differential mobility analysis (ES-DMA), was used to… read more here.

Keywords: aggregation; mobility analysis; differential mobility; electrospray differential ... See more keywords
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Nano electrospray differential mobility analysis based size-selection of liposomes and very-low density lipoprotein particles for offline hyphenation to MALDI mass spectrometry.

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Published in 2019 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2019.112998

Abstract: Gas-phase electrophoresis of single-charged analytes (nanoparticles) enables their separation according to the surface-dry particle size (Electrophoretic Mobility Diameter, EMD), which corresponds to the diameter of spherical shaped particles. Employing a nano Electrospray Differential Mobility Analyzer… read more here.

Keywords: mobility; electrospray differential; nano electrospray; differential mobility ... See more keywords
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Differential mobility spectrometry imaging for pathological applications.

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Published in 2020 at "Experimental and molecular pathology"

DOI: 10.1016/j.yexmp.2020.104526

Abstract: Pathologic examination of clinical tissue samples is time consuming and often does not involve the comprehensive analysis of the whole specimen. Automated tissue analysis systems have potential to make the workflow of a pathologist more… read more here.

Keywords: spectrometry; differential mobility; tissue; mobility spectrometry ... See more keywords
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Laser desorption tissue imaging with Differential Mobility Spectrometry.

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Published in 2022 at "Experimental and molecular pathology"

DOI: 10.1016/j.yexmp.2022.104759

Abstract: Pathological gross examination of breast carcinoma samples is sometimes laborious. A tissue pre-mapping method could indicate neoplastic areas to the pathologist and enable focused sampling. Differential Mobility Spectrometry (DMS) is a rapid and affordable technology… read more here.

Keywords: breast; mobility spectrometry; tissue; differential mobility ... See more keywords
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Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring.

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Published in 2021 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.1c02826

Abstract: Modern biomarker and translational research as well as personalized health care studies rely heavily on powerful omics' technologies, including metabolomics and lipidomics. However, to translate metabolomics and lipidomics discoveries into a high-throughput clinical setting, standardization… read more here.

Keywords: mobility spectrometry; reaction monitoring; multiple reaction; standardization ... See more keywords
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Argentination: A Silver Bullet for Cannabinoid Separation by Differential Mobility Spectrometry.

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Published in 2023 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.3c01241

Abstract: As the legality of cannabis continues to evolve globally, there is a growing demand for methods that can accurately quantitate cannabinoids found in commercial products. However, the isobaric nature of many cannabinoids, along with variations… read more here.

Keywords: fragmentation; argentination; differential mobility; spectrometry ... See more keywords
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Absolute Quantification of Bionanoparticles by Electrospray Differential Mobility Analysis: An Application to Lipoprotein Particle Concentration Measurements.

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Published in 2017 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.6b02909

Abstract: This study presents an upgraded electrospray differential mobility analysis (ES-DMA) setup for the absolute quantification of bionanoparticle concentrations in biological samples, with a special focus on non-high-density-lipoprotein particle concentrations (non-HDL-P). Metrological characterization of the system's… read more here.

Keywords: mobility analysis; differential mobility; electrospray differential; particle ... See more keywords
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Identifying Fenton-Reacted Trimethoprim Transformation Products Using Differential Mobility Spectrometry.

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Published in 2018 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.8b00484

Abstract: A transformation product of trimethoprim, a contaminant of emerging concern in the environment, is generated using an electro-assisted Fenton reaction and analyzed using differential mobility spectrometry (DMS) in combination with MS/MS techniques and quantum chemical… read more here.

Keywords: differential mobility; transformation; mobility spectrometry; using differential ... See more keywords