Differential Regulation of MeCP2 Phosphorylation by Laminin in Oligodendrocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0939-4
Abstract: Oligodendrocytes (OLGs) are the myelinating cells of the central nervous system (CNS), and its proper differentiation is crucial for normal functioning of neurons. Methyl-CpG-binding protein 2 (MeCP2) is a multifunctional methylated DNA binding protein; mutation… read more here.
Keywords: mecp2; differential regulation; laminin; mecp2 phosphorylation ... See more keywords
Differential regulation analysis reveals dysfunctional regulatory mechanism involving transcription factors and microRNAs in gastric carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Artificial intelligence in medicine"
DOI: 10.1016/j.artmed.2017.02.006
Abstract: Gastric cancer (GC) is one of the most incident malignancies in the world. Although lots of featured genes and microRNAs (miRNAs) have been identified to be associated with gastric carcinogenesis, underlying regulatory mechanisms still remain… read more here.
Keywords: analysis; differential regulation; gastric carcinogenesis; genes mirnas ... See more keywords
Non-Canonical Interaction between Calmodulin and Calcineurin Contributes to the Differential Regulation of Plant-Derived Calmodulins on Calcineurin.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.1c00873
Abstract: Calmodulin (CaM) serves as an important Ca2+ signaling hub that regulates many protein signaling pathways. Recently, it was demonstrated that plant CaM homologues can regulate mammalian targets, often in a manner that opposes the impact… read more here.
Keywords: cam; plant; plant derived; calmodulin ... See more keywords
Differential regulation of alcohol consumption and reward by the transcriptional cofactor LMO4
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0706-8
Abstract: Repeated alcohol exposure leads to changes in gene expression that are thought to underlie the transition from moderate to excessive drinking. However, the mechanisms by which these changes are integrated into a maladaptive response that… read more here.
Keywords: alcohol consumption; consumption reward; differential regulation; regulation alcohol ... See more keywords
Differential regulation of vaginal lipocalins (OBP, MUP) during the estrous cycle of the house mouse
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12021-2
Abstract: Female house mice produce pheromone-carrying major urinary proteins (MUPs) in a cycling manner, thus reaching the maximum urinary production just before ovulation. This is thought to occur to advertise the time of ovulation via deposited… read more here.
Keywords: vaginal lipocalins; house mouse; cycle; differential regulation ... See more keywords
Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy152
Abstract: Aims In heart failure (HF), enhanced persistent Na+ current (INaL) exerts detrimental effects on cellular electrophysiology and can induce arrhythmias. However, the underlying regulatory mechanisms remain unclear. Our aim was to potentially investigate the regulation… read more here.
Keywords: regulation sodium; heart; differential regulation; human failing ... See more keywords
Differential regulation of physiological activities by RcsB and OmpR in Yersinia enterocolitica.
Sign Up to like & getrecommendations! Published in 2019 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnz210
Abstract: A thorough understanding of the mechanisms of Rcs and EnvZ/OmpR phosphorelay systems that allow Yersinia enterocolitica to thrive in various environments is crucial to prevent and control Y. enterocolitica infections. In this study, we showed… read more here.
Keywords: biofilm formation; rcsb ompr; differential regulation; yersinia enterocolitica ... See more keywords
Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Pharmacology"
DOI: 10.1111/bph.16035
Abstract: Cannabinoids are a promising therapeutic avenue for chronic pain. However, clinical trials often fail to report analgesic efficacy of cannabinoids. Inhibition of voltage gate calcium (Cav) channels is one mechanism through which cannabinoids may produce… read more here.
Keywords: calcium; cav3 cav2; cav2 calcium; calcium channels ... See more keywords
Sex‐based differential regulation of bacterial‐induced bone resorption
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Periodontal Research"
DOI: 10.1111/jre.12401
Abstract: BACKGROUND AND OBJECTIVE Periodontal disease pathogenesis is comprised of the complex inflammatory immune response to oral bacterial dysbiosis. Like other inflammatory diseases, there is sexual dimorphism evident in periodontal diseases. During periodontitis, inflammatory chemokines direct… read more here.
Keywords: response; differential regulation; sex based; expression ... See more keywords
Differential Regulation of Cardiac Function and Intracardiac Cytokines by Rapamycin in Healthy and Diabetic Rats
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/5724046
Abstract: Diabetes is comorbid with cardiovascular disease and impaired immunity. Rapamycin improves cardiac functions and extends lifespan by inhibiting the mechanistic target of rapamycin complex 1 (mTORC1). However, in diabetic murine models, Rapamycin elevates hyperglycemia and… read more here.
Keywords: cytokines rapamycin; intracardiac cytokines; cardiac function; differential regulation ... See more keywords
Differential Regulation of NK Cell Receptors in Acute Lymphoblastic Leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/7972039
Abstract: Cancer immunotherapies are preferred over conventional treatments which are highly cytotoxic to normal cells. Focus has been on T cells but natural killer (NK) cells have equal potential. Concepts in cancer control and influence of… read more here.
Keywords: cell; lymphoblastic leukemia; acute lymphoblastic; differential regulation ... See more keywords