Titanium dioxide nanoparticles translocate through differentiated Caco‐2 cell monolayers, without disrupting the barrier functionality or inducing genotoxic damage
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DOI: 10.1002/jat.3630
Abstract: The widespread use of titanium dioxide nanoparticles (TiO2NPs) in commercial food products makes intestinal cells a suitable target. Accordingly, we have used the human colon adenocarcinoma Caco‐2 cells to detect their potential harmful effects. Caco‐2… read more here.
Keywords: microscopy; cell monolayers; titanium dioxide; dioxide nanoparticles ... See more keywords
Modulation of Intestinal Epithelial Permeability in Differentiated Caco-2 Cells Exposed to Aflatoxin M1 and Ochratoxin A Individually or Collectively
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DOI: 10.3390/toxins10010013
Abstract: Aflatoxin M1 (AFM1) and ochratoxin A (OTA) are mycotoxins commonly found in milk; however, their effects on intestinal epithelial cells have not been reported. In the present study, we show that AFM1 (0.12 and 12… read more here.
Keywords: intestinal epithelial; caco cells; epithelial permeability; differentiated caco ... See more keywords
Transcriptome Analysis of Ochratoxin A-Induced Apoptosis in Differentiated Caco-2 Cells
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DOI: 10.3390/toxins12010023
Abstract: Ochratoxin A (OTA), an important mycotoxin that occurs in food and animal feed, has aroused widespread concern in recent years. Previous studies have indicated that OTA causes nephrotoxicity, hepatotoxicity, genotoxicity, immunotoxicity, cytotoxicity, and neurotoxicity. The… read more here.
Keywords: transcriptome analysis; apoptosis differentiated; caco cells; analysis ... See more keywords