Organization of cortical microtubules in differentiated cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.31011
Abstract: The microtubule cytoskeleton plays a critical role in a variety of cellular activities, and its structures and functions have been extensively studied. However, little is known about cell differentiation-related microtubule remodeling, its regulatory mechanisms, and… read more here.
Keywords: differentiated cells; cell differentiation; organization cortical; microtubule ... See more keywords
The Effects of Progenitor and Differentiated Cells on Ectopic Calcification of Engineered Vascular Tissues.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.08.019
Abstract: Ectopic vascular calcification associated with aging, diabetes mellitus, atherosclerosis, and chronic kidney disease is a considerable risk factor for cardiovascular events and death. Although vascular smooth muscle cells are primarily implicated in calcification, the role… read more here.
Keywords: vascular tissues; ectopic calcification; calcification engineered; calcification ... See more keywords
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109992
Abstract: To elucidate mechanisms by which T cells eliminate leukemia, we study donor lymphocyte infusion (DLI), an established immunotherapy for relapsed leukemia. We model T cell dynamics by integrating longitudinal, multimodal data from 94,517 bone marrow-derived single T cell… read more here.
Keywords: single cell; evolution cell; mapping evolution; therapy ... See more keywords
Direct reprogramming of terminally differentiated cells into neurons: A novel and promising strategy for Alzheimer's disease treatment
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2019.109820
Abstract: Glial activation is a common pathological process of the central nervous system (CNS) in disorders such as Alzheimer's disease (AD). Several approaches have been used to reduce the number of activated astrocytes and microglia in… read more here.
Keywords: alzheimer disease; cells neurons; direct reprogramming; terminally differentiated ... See more keywords
Redox environment in stem and differentiated cells: A quantitative approach
Sign Up to like & getrecommendations! Published in 2017 at "Redox Biology"
DOI: 10.1016/j.redox.2017.04.016
Abstract: Stem cells are believed to maintain a specific intracellular redox status through a combination of enhanced removal capacity and limited production of ROS. In the present study, we challenge this assumption by developing a quantitative… read more here.
Keywords: redox; quantitative approach; stem differentiated; stem ... See more keywords
Pluripotent cells display enhanced resistance to mutagenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Stem cell research"
DOI: 10.1016/j.scr.2016.12.029
Abstract: Pluripotent cells have been reported to exhibit lower frequencies of point mutations and higher levels of DNA repair than differentiated cells. This predicts that pluripotent cells are less susceptible to mutagenic exposures than differentiated cells.… read more here.
Keywords: pluripotent cells; point mutations; pluripotent; cells display ... See more keywords
Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2017.03.012
Abstract: (Cell Stem Cell 12, 407–412; April 4, 2013) It came to our attention following reader queries that some of the immunofluorescence image panels presented in this paper contained images that overlap with each other, with… read more here.
Keywords: response differentiated; cells derived; lack immune; immune response ... See more keywords
A Lin28 homologue reprograms differentiated cells to stem cells in the moss Physcomitrella patens
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14242
Abstract: Both land plants and metazoa have the capacity to reprogram differentiated cells to stem cells. Here we show that the moss Physcomitrella patens Cold-Shock Domain Protein 1 (PpCSP1) regulates reprogramming of differentiated leaf cells to… read more here.
Keywords: moss physcomitrella; cells stem; physcomitrella patens; stem cells ... See more keywords
Effect of iron overload from multi walled carbon nanotubes on neutrophil-like differentiated HL-60 cells
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38598-4
Abstract: Multi walled carbon nanotubes (MWCNTs) are one of the most intensively explored nanomaterials because of their unique physical and chemical properties. Due to the widespread use of MWCNTs, it is important to investigate their effects… read more here.
Keywords: like differentiated; iron overload; neutrophil like; iron ... See more keywords
Robust detection of undifferentiated iPSC among differentiated cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66845-6
Abstract: Recent progress in human induced pluripotent stem cells (iPSC) technologies suggest that iPSC application in regenerative medicine is a closer reality. Numerous challenges prevent iPSC application in the development of numerous tissues and for the… read more here.
Keywords: detection; residual undifferentiated; undifferentiated ipsc; cell ... See more keywords
Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid–Induced Differentiation in Motor Neuron–Like NSC-34 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000492653
Abstract: Background/Aims: Intermediate-conductance Ca2+-activated K+ (IKCa; KCa3.1 or KCNN4) channels affect the behaviors of central neurons including motor neurons. The mechanism through which neuronal differentiation is related to the activity of these channels remains largely unclear.… read more here.
Keywords: induced differentiation; activity; nsc cells; ikca channels ... See more keywords