Cytoproliferative activity in colorectal poorly differentiated clusters: Biological significance in tumor setting.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2021.151772
Abstract: BACKGROUND Poorly differentiated clusters (PDCs) have gained a significant prognostic role in colorectal carcinomas (CRCs) being associated to high risk of lymph node metastasis, shorter survival time and poor prognosis. The knowledge in PDC biology… read more here.
Keywords: poorly differentiated; activity colorectal; cytoproliferative activity; differentiated clusters ... See more keywords
Poorly Differentiated Clusters: Clinical Impact in Colorectal Cancer
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DOI: 10.1016/j.clcc.2016.06.002
Abstract: Abstract Colorectal cancer (CRC) is one of the most common malignancies worldwide and it still represents a major cause of cancer‐related death. Postsurgical Tumor Node Metastasis (pTNM) stage is the main prognostic factor in CRC… read more here.
Keywords: poorly differentiated; colorectal cancer; differentiated clusters; crc ... See more keywords
Clinicopathological significance of heterogeneic ezrin expression in poorly differentiated clusters of colorectal cancers
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DOI: 10.1111/cas.14093
Abstract: Multicellular structures, such as tumor buddings and poorly differentiated clusters (PDC), exist at the invasive front of colorectal cancers (CRC). Although it has been reported that CRC with PDC showed frequent lymph node metastases with… read more here.
Keywords: ezrin expression; poorly differentiated; pdc; differentiated clusters ... See more keywords
Histological grading based on poorly differentiated clusters is predictive of tumour response and clinical outcome in rectal carcinoma treated with neoadjuvant chemoradiotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Histopathology"
DOI: 10.1111/his.13242
Abstract: The clinical outcome of patients with locally advanced rectal cancer who undergo neoadjuvant chemoradiotherapy (CRT) is influenced by the tumour response to treatment, which is reflected by tumour regression grade and post‐treatment (y) TNM stage.… read more here.
Keywords: poorly differentiated; neoadjuvant chemoradiotherapy; differentiated clusters; treated neoadjuvant ... See more keywords
Lymph Node Tumor Burden Correlates With Tumor Budding and Poorly Differentiated Clusters: A New Prognostic Factor in Colorectal Carcinoma?
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DOI: 10.14309/ctg.0000000000000303
Abstract: INTRODUCTION: Molecular lymph node (LN) staging in early colorectal cancer (CRC) has demonstrated to be more precise than conventional histopathology pN staging. Tumor budding (TB) and poorly differentiated clusters (PDCs) are associated with LN metastases,… read more here.
Keywords: poorly differentiated; differentiated clusters; crc; lymph node ... See more keywords
Tumor Budding and Poorly Differentiated Clusters in Small Intestinal Adenocarcinoma
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DOI: 10.3390/cancers12082199
Abstract: The clinicopathologic and prognostic significances of tumor budding (TB) and poorly-differentiated clusters (PDC) have not been investigated in small intestinal adenocarcinomas (SIACs). In 236 surgically-resected SIACs, we counted TB (single cells or clusters ≤4 tumor… read more here.
Keywords: poorly differentiated; small intestinal; grade; differentiated clusters ... See more keywords
Prognostic Ability of Tumor Budding Outperforms Poorly Differentiated Clusters in Gastric Cancer
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DOI: 10.3390/cancers14194731
Abstract: Simple Summary Small clusters of tumor cells at the invasion front of the tumor, known as “tumor budding” and larger clusters of cells, known as “poorly differentiated clusters”, are well known histological parameters to assess… read more here.
Keywords: tumor budding; differentiated clusters; gastric cancer; poorly differentiated ... See more keywords