MDM4 amplification in atypical lipomatous tumors/well‐differentiated liposarcoma: Private event or alternative oncogenic mechanism?
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.1002/gcc.23130
Abstract: Adipocytic tumors are the most common mesenchymal tumors in soft tissues. Among them, a diagnostic challenge relies in the distinction between lipoma and atypical lipomatous tumor (ALT)/well differentiated liposarcoma (WDLPS), as both entities are often… read more here.
Keywords: mdm4 amplification; differentiated liposarcoma; amplification; event alternative ... See more keywords
The clinical behavior of well differentiated liposarcoma can be extremely variable: A retrospective cohort study at a major sarcoma center
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DOI: 10.1002/jso.25082
Abstract: The pathogenesis of well differentiated liposarcoma (WDLPS) is poorly understood and pathologic characterization is often challenging. Descriptive terms (such as sclerosing, myxoid, inflammatory, spindle cell) are frequently encountered in the pathology reports and are of… read more here.
Keywords: behavior well; clinical behavior; liposarcoma extremely; well differentiated ... See more keywords
Well-differentiated liposarcoma disguised as a recurrent lipoma of the forearm flexor compartment: A case report
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2020.05.063
Abstract: Highlights • The giant size and other unusual characteristics raised the awareness of malignant lipomatous mass.• Differential diagnosis between giant lipoma and liposarcoma is of great importance.• Post-operative histopathological diagnosis was well-differentiated liposarcoma lipoma-like. read more here.
Keywords: liposarcoma disguised; liposarcoma; case; well differentiated ... See more keywords
Atypical lipomatous tumour/well-differentiated liposarcoma found in the buccal mucosa: A rare case report.
Sign Up to like & getrecommendations! Published in 2022 at "Gerodontology"
DOI: 10.1111/ger.12620
Abstract: Oral liposarcomas are uncommon diseases, the most predominant histopathological subtype being atypical lipomatous tumour/well-differentiated liposarcoma. In regard to its clinical aspects in the oral cavity, it is challenging to confirm a diagnosis and develop a… read more here.
Keywords: lipomatous tumour; tumour well; differentiated liposarcoma; well differentiated ... See more keywords
Evaluation of Efficacy of Adjuvant Radiotherapy in Well-Differentiated Liposarcoma Patients with Positive Surgical Margins: A Population-based Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/5735679
Abstract: Background The use of adjuvant radiotherapy (RT) for well-differentiated liposarcoma (WD-LPS) patients with positive surgical margins is unclear. We aim to compare the overall survival (OS) and cancer-specific survival (CSS) of well-differentiated liposarcoma patients with… read more here.
Keywords: surgical margins; css; differentiated liposarcoma; patients positive ... See more keywords
Well-Differentiated Liposarcoma Localized to the Thyroid Gland
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DOI: 10.1159/000490346
Abstract: Liposarcoma of the thyroid gland is a pathology that is rarely encountered in clinical practice, given the paucity of these cases. For the same reason, a definite treatment protocol has not been established for these… read more here.
Keywords: thyroid gland; well differentiated; differentiated liposarcoma; pathology ... See more keywords
Well Differentiated Liposarcoma Presenting as a Duodenal Polyp: A Case Report and Review of the Literature
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Surgical Pathology"
DOI: 10.1177/10668969221099628
Abstract: Liposarcoma is the most common malignant soft tissue tumour in adults occurring predominantly in the retroperitoneum and extremities but very rarely within the gastrointestinal tract. We report on a 77-year-old gentleman who presented with a… read more here.
Keywords: duodenal polyp; differentiated liposarcoma; report; polyp ... See more keywords
Integrated genomic and transcriptomic analysis revealed mutation patterns of de-differentiated liposarcoma and leiomyosarcoma
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DOI: 10.1186/s12885-020-07456-2
Abstract: Background Treating patients with advanced sarcomas is challenging due to great histologic diversity among its subtypes. Leiomyosarcoma (LMS) and de-differentiated liposarcoma (DDLPS) are two common and aggressive subtypes of soft tissue sarcoma (STS). They differ… read more here.
Keywords: lms ddlps; fusion events; differentiated liposarcoma; analysis revealed ... See more keywords
ASO Author Reflections: Surveillance After Resection of Retroperitoneal Well-Differentiated Liposarcoma: A Balancing Act Between Earlier Recurrence Detection, Patient Anxiety, and Health Care Resource Expenditure
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DOI: 10.1245/s10434-020-08597-1
Abstract: Well-differentiated liposarcoma (WDLPS) is the most common subtype of soft tissue sarcoma occurring in the retroperitoneum. Although complete macroscopic resection is the only potentially curative treatment, locoregional recurrences are common and occur in up to… read more here.
Keywords: detection; recurrence; surveillance; well differentiated ... See more keywords