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Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc02060e
Abstract: Differentiating amyloid beta (Aβ) subspecies Aβ40 and Aβ42 has long been considered an impossible mission with small-molecule probes. In this report, based on recently published structures of Aβ fibrils, we designed iminocoumarin–thiazole (ICT) fluorescence probes…
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Keywords:
differentiating amyloid;
fluorescence;
small molecule;
amyloid plaques ... See more keywords