MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway
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DOI: 10.3389/fgene.2021.783352
Abstract: Objective: Osteoporosis is caused by the dysregulation of bone homeostasis which is synergistically mediated by osteoclasts and osteoblasts. MiR-27a-3p is a key inhibitor of bone formation. Hence, unearthing the downstream target gene of miR-27a-3p is… read more here.
Keywords: differentiation autophagy; pre osteoblasts; inflammatory factors; differentiation ... See more keywords
miR-103-3p Regulates the Differentiation and Autophagy of Myoblasts by Targeting MAP4
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24044130
Abstract: Skeletal muscle is the most abundant tissue in mammals, and myogenesis and differentiation require a series of regulatory factors such as microRNAs (miRNAs). In this study, we found that miR-103-3p was highly expressed in the… read more here.
Keywords: differentiation; c2c12 cells; mir 103; differentiation autophagy ... See more keywords