Thermosensitive Injectable Gradient Hydrogel-Induced Bidirectional Differentiation of BMSCs.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200250
Abstract: Osteochondral defects threaten the quality of life of patients to a great extent. To simulate gradient changes of osteochondral tissue, we design a gradient-mixing injection device consisting of a controller and injection pumps. Bioactive glass… read more here.
Keywords: thermosensitive injectable; differentiation bmscs; gradient hydrogels; gradient hydrogel ... See more keywords
TP53-mediated miR-2861 promotes osteogenic differentiation of BMSCs by targeting Smad7.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04276-1
Abstract: Bone defect seriously affects the quality of life. Meanwhile, osteogenic differentiation in BMSCs could regulate the progression of bone defect. Transcription factors are known to regulate the osteogenic differentiation in BMSCs. The study aimed to… read more here.
Keywords: differentiation bmscs; osteogenic differentiation; mir 2861; bmscs ... See more keywords
Promotive Role of CircATRNL1 on Chondrogenic Differentiation of BMSCs mediated by miR-338-3p.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2021.02.003
Abstract: AIM Bone marrow mesenchymal stem cells (BMSCs) are ideal seed cells for tissue engineering cartilage construction. However, the underlying mechanism of it has not been illuminate well. In this study, the effects of circATRNL1 (hsa_circ_0020093)… read more here.
Keywords: differentiation bmscs; chondrogenic differentiation; differentiation; mir 338 ... See more keywords
YY1-induced lncRNA XIST inhibits cartilage differentiation of BMSCs by binding with TAF15 to stabilizing FUT1 expression
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2022.02.002
Abstract: Introduction The functional roles and mechanism of the XIST in osteoarthritis and the chondrogenic differentiation of BMSCs were clarified. Methods The expression levels of XIST, TAF15, FUT1 and YY1 were detected through quantitative RT-PCR. The… read more here.
Keywords: chondrogenic differentiation; differentiation; differentiation bmscs; xist ... See more keywords
Graphene/Si Promoted Osteogenic Differentiation of BMSCs through Light Illumination.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b14679
Abstract: Graphene (Gr) presents promising applications in regulating the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Light illumination is regarded as a spatiotemporally controllable, easily applicable and noninvasive mean to modulate materials' responses. Herein,… read more here.
Keywords: light illumination; differentiation bmscs; differentiation; osteogenic differentiation ... See more keywords
Adapting to the acidic environment of the NP: RADA16-PLGA (TGF-β3) induces chondrogenic differentiation of BMSCs.
Sign Up to like & getrecommendations! Published in 2024 at "Nanomedicine"
DOI: 10.1080/17435889.2024.2372242
Abstract: Aim: RADA16-PLGA composite scaffolds constructed with simultaneous loading of BMSCs and TGF-β3 and explored their ability for chondrogenic differentiation in vitro.Methods: The performance of the composite scaffolds is assessed by rheometer assay, electron microscopic structural… read more here.
Keywords: differentiation; differentiation bmscs; rada16 plga; composite scaffolds ... See more keywords
Porphyromonas gingivalis OMVs inhibit osteogenic differentiation of BMSCs via SAA3/TLR4/MyD88/NF-κB axis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2025.2540823
Abstract: ABSTRACT Backgrounds Periodontitis-induced alveolar bone loss is a primary cause of tooth loss. Porphyromonas gingivalis (P. gingivalis) is the primary pathogenic bacterium of periodontitis. Outer membrane vesicles (OMVs) derived from P. gingivalis (P.g-OMVs) contain various… read more here.
Keywords: osteogenic differentiation; differentiation bmscs; tlr4 myd88; differentiation ... See more keywords
MicroRNA‐99a is a novel regulator of KDM6B‐mediated osteogenic differentiation of BMSCs
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13490
Abstract: Skeletal tissue originates from mesenchymal stem cells (MSCs) with differentiation potential into the osteoblast lineage regulated by essential transcriptional and post‐transcriptional mechanisms. Recently, miRNAs and histone modifications have been identified as novel key regulators of… read more here.
Keywords: differentiation bmscs; mir 99a; differentiation; osteogenic differentiation ... See more keywords
Osterix mRNA Enrichment in Small Extracellular Vesicles Derived From Osteogenically Induced ADSCs: A Promoter of Osteogenic Differentiation in BMSCs
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.70353
Abstract: Osteogenic differentiation of bone marrow stem cells (BMSCs) is essential for bone tissue regeneration and repair. However, this process is often hindered by an unstable differentiation influenced by local microenvironmental factors. While small extracellular vesicles… read more here.
Keywords: differentiation; differentiation bmscs; osterix mrna; adsc sevs ... See more keywords
Excessive mechanical stress induced temporomandibular joint osteoarthritis via osteoclasts-mediated osteogenic differentiation of BMSCs.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13360
Abstract: BACKGROUND Bone homeostasis is a dynamic process maintained by osteoblasts and osteoclasts, which may be regulated by excessive mechanical stress (EMS). OBJECTIVES Our study aims to explore the relationship between osteogenic differentiation of BMSCs and… read more here.
Keywords: differentiation bmscs; mechanical stress; excessive mechanical; osteogenic differentiation ... See more keywords
Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-022-05295-9
Abstract: Background The aim of this study was to investigate the role of Vaspin on the chondrogenic differentiation of bone mesenchymal stem cells (BMSCs), and its effect on chondrocyte survival and ECM secretion. We also assessed… read more here.
Keywords: differentiation; chondrogenic differentiation; vaspin; akt activation ... See more keywords