Thermosensitive Injectable Gradient Hydrogel-Induced Bidirectional Differentiation of BMSCs.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200250
Abstract: Osteochondral defects threaten the quality of life of patients to a great extent. To simulate gradient changes of osteochondral tissue, we design a gradient-mixing injection device consisting of a controller and injection pumps. Bioactive glass… read more here.
Keywords: thermosensitive injectable; differentiation bmscs; gradient hydrogels; gradient hydrogel ... See more keywords
TP53-mediated miR-2861 promotes osteogenic differentiation of BMSCs by targeting Smad7.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04276-1
Abstract: Bone defect seriously affects the quality of life. Meanwhile, osteogenic differentiation in BMSCs could regulate the progression of bone defect. Transcription factors are known to regulate the osteogenic differentiation in BMSCs. The study aimed to… read more here.
Keywords: differentiation bmscs; osteogenic differentiation; mir 2861; bmscs ... See more keywords
Promotive Role of CircATRNL1 on Chondrogenic Differentiation of BMSCs mediated by miR-338-3p.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2021.02.003
Abstract: AIM Bone marrow mesenchymal stem cells (BMSCs) are ideal seed cells for tissue engineering cartilage construction. However, the underlying mechanism of it has not been illuminate well. In this study, the effects of circATRNL1 (hsa_circ_0020093)… read more here.
Keywords: differentiation bmscs; chondrogenic differentiation; differentiation; mir 338 ... See more keywords
YY1-induced lncRNA XIST inhibits cartilage differentiation of BMSCs by binding with TAF15 to stabilizing FUT1 expression
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2022.02.002
Abstract: Introduction The functional roles and mechanism of the XIST in osteoarthritis and the chondrogenic differentiation of BMSCs were clarified. Methods The expression levels of XIST, TAF15, FUT1 and YY1 were detected through quantitative RT-PCR. The… read more here.
Keywords: chondrogenic differentiation; differentiation; differentiation bmscs; xist ... See more keywords
Graphene/Si Promoted Osteogenic Differentiation of BMSCs through Light Illumination.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b14679
Abstract: Graphene (Gr) presents promising applications in regulating the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Light illumination is regarded as a spatiotemporally controllable, easily applicable and noninvasive mean to modulate materials' responses. Herein,… read more here.
Keywords: light illumination; differentiation bmscs; differentiation; osteogenic differentiation ... See more keywords
MicroRNA‐99a is a novel regulator of KDM6B‐mediated osteogenic differentiation of BMSCs
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13490
Abstract: Skeletal tissue originates from mesenchymal stem cells (MSCs) with differentiation potential into the osteoblast lineage regulated by essential transcriptional and post‐transcriptional mechanisms. Recently, miRNAs and histone modifications have been identified as novel key regulators of… read more here.
Keywords: differentiation bmscs; mir 99a; differentiation; osteogenic differentiation ... See more keywords
Excessive mechanical stress induced temporomandibular joint osteoarthritis via osteoclasts-mediated osteogenic differentiation of BMSCs.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13360
Abstract: BACKGROUND Bone homeostasis is a dynamic process maintained by osteoblasts and osteoclasts, which may be regulated by excessive mechanical stress (EMS). OBJECTIVES Our study aims to explore the relationship between osteogenic differentiation of BMSCs and… read more here.
Keywords: differentiation bmscs; mechanical stress; excessive mechanical; osteogenic differentiation ... See more keywords
Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-022-05295-9
Abstract: Background The aim of this study was to investigate the role of Vaspin on the chondrogenic differentiation of bone mesenchymal stem cells (BMSCs), and its effect on chondrocyte survival and ECM secretion. We also assessed… read more here.
Keywords: differentiation; chondrogenic differentiation; vaspin; akt activation ... See more keywords
The Emerging Role of Non-Coding RNAs in Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.903278
Abstract: Autologous bone marrow-derived mesenchymal stem cells (BMSCs) are more easily available and frequently used for bone regeneration in clinics. Osteogenic differentiation of BMSCs involves complex regulatory networks affecting bone formation phenomena. Non-coding RNAs (ncRNAs) refer… read more here.
Keywords: differentiation bmscs; bone; osteogenic differentiation; differentiation ... See more keywords
HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065686
Abstract: Bone marrow-derived mesenchymal stem cells (BMSCs) can differentiate into hepatocyte-like cells (HLCs) to alleviate acute liver injury (ALI). Herpetfluorenone (HPF), as an active ingredient in the dried, mature seeds Herpetospermum caudigerum Wall, used in Tibetan… read more here.
Keywords: hpf; differentiation bmscs; bmscs hlcs; bmscs ... See more keywords
Peroxisome proliferator-activated receptor-γ and its related pathway in bone marrow mesenchymal stem cell differentiation co-cultured with mechanically stretched ligament fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2018.3578
Abstract: The occurrence of pelvic floor dysfunctional disease (PFD) is closely related with elasticity, toughness, and functional changes of the connective tissue of the pelvic support tissue. Bone marrow mesenchymal stem cells (BMSCs) have been confirmed… read more here.
Keywords: ppar; differentiation bmscs; differentiation; cell ... See more keywords