Tuba8 Drives Differentiation of Cortical Radial Glia into Apical Intermediate Progenitors by Tuning Modifications of Tubulin C Termini.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.01.036
Abstract: Most adult neurons and glia originate from radial glial progenitors (RGs), a type of stem cell typically extending from the apical to the basal side of the developing cortex. Precise regulation of the choice between… read more here.
Keywords: apical intermediate; differentiation cortical; drives differentiation; tuba8 drives ... See more keywords
Transcription Factors Bcl11a and Bcl11b Are Required for the Production and Differentiation of Cortical Projection Neurons.
Sign Up to like & getrecommendations! Published in 2021 at "Cerebral cortex"
DOI: 10.1093/cercor/bhab437
Abstract: The generation and differentiation of cortical projection neurons are extensively regulated by interactive programs of transcriptional factors. Here, we report the cooperative functions of transcription factors Bcl11a and Bcl11b in regulating the development of cortical… read more here.
Keywords: projection neurons; differentiation cortical; bcl11a bcl11b; projection ... See more keywords
Reg-1α Promotes Differentiation of Cortical Progenitors via Its N-Terminal Active Domain
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00681
Abstract: Reg-1α belongs to the Reg family of small, secreted proteins expressed in both pancreas and nervous system. Reg-1α is composed of two domains, an insoluble C-type lectin domain and a short soluble N-terminal peptide, which… read more here.
Keywords: differentiation cortical; reg promotes; cortical progenitors; progenitors via ... See more keywords