Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2424
Abstract: Elevated concentrations of growth differentiation factor 15 (GDF‐15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF‐15 concentrations represent remains unclear. Here, we aim… read more here.
Keywords: heart failure; differentiation factor; growth differentiation; patients heart ... See more keywords
Plasma growth differentiation factor‐15 in patients with “lone” atrial fibrillation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24373
Abstract: Growth differentiation factor‐15 (GDF‐15) is a member of the transforming growth factor β superfamily, correlated with various stimuli, including cardiovascular disease. The association between plasma GDF‐15 level and “lone” AF, that is, AF of unknown… read more here.
Keywords: growth; differentiation factor; growth differentiation; factor ... See more keywords
Low plasma growth/differentiation factor 1 levels are associated with liver fibrosis in patients with stable angina
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24745
Abstract: Growth differentiation factor 1 (GDF1) is a member of the transforming growth factor‐β (TGF‐β) superfamily and a protective mediator against the development of post‐infarction cardiac remodeling by negatively regulating MEK‐ERK1/2 and Smad signaling pathways in… read more here.
Keywords: differentiation factor; fibrosis; liver fibrosis; growth differentiation ... See more keywords
Associations of device‐measured sleep, sedentariness and physical activity with growth differentiation factor 15 in older adults
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12924
Abstract: Growth differentiation factor 15 (GDF‐15) is a biomarker for chronic disease burden that might explain the health effects of sedentary behaviours (SBs) and physical activity (PA). We examined associations of device‐measured sleep, SB and PA,… read more here.
Keywords: differentiation factor; growth differentiation; physical activity; associations device ... See more keywords
Role of Mass Spectrometry in Investigating a Novel Protein: The Example of Tumor Differentiation Factor (TDF).
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-15950-4_24
Abstract: Better understanding of central nervous system (CNS) molecules can include the identification of new molecules and their receptor systems. Discovery of novel proteins and elucidation of receptor targets can be accomplished using mass spectrometry (MS).… read more here.
Keywords: tumor differentiation; differentiation factor; tdf; mass spectrometry ... See more keywords
Associations Between Plasma Growth and Differentiation Factor-15 with Aging Phenotypes in Muscle, Adipose Tissue, and Bone.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-021-00912-6
Abstract: Growth and differentiation factor 15 (GDF-15) is associated with muscle, fat, and bone metabolism; however, this association has not been well characterized. Plasma GDF-15, appendicular skeletal muscle mass (ASM), fat mass (FM), and bone mineral… read more here.
Keywords: muscle; differentiation factor; bone; growth differentiation ... See more keywords
Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Research in Cardiology"
DOI: 10.1007/s00392-020-01597-x
Abstract: Background Dialysis patients are at increased risk of HF. However, diagnostic utility of NT-proBNP as a biomarker is decreased in patients on dialysis. GDF-15 and cNEP are biomarkers of distinct mechanisms that may contribute to… read more here.
Keywords: differentiation factor; growth differentiation; heart failure; dialysis patients ... See more keywords
Biomechanical stress in myocardial infarctions: can endothelin-1 and growth differentiation factor 15 serve as immunohistochemical markers?
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-017-1726-z
Abstract: Myocardial infarctions go along with biomechanical stress, i.e. stretching of muscle fibres, and the expression of certain marker molecules. We tested if two of those markers, endothelin-1 (ET-1) and growth differentiation factor 15 (GDF-15), can… read more here.
Keywords: myocardial infarctions; endothelin growth; immunohistochemical markers; differentiation factor ... See more keywords
A recurrent, non-penetrant sequence variant, p.Arg266Cys in Growth/Differentiation Factor 3 (GDF3) in a female with unilateral anophthalmia and skeletal anomalies
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2017.06.006
Abstract: Purpose The genetic causes of anophthalmia, microphthalmia and coloboma remain poorly understood. Missense mutations in Growth/Differentiation Factor 3 (GDF3) gene have previously been reported in patients with microphthalmia, iridial and retinal colobomas, Klippel-Feil anomaly with… read more here.
Keywords: factor gdf3; differentiation factor; female unilateral; unilateral anophthalmia ... See more keywords
Growth differentiation factor 11 improves neurobehavioral recovery and stimulates angiogenesis in rats subjected to cerebral ischemia/reperfusion
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2018.02.011
Abstract: The recent suggestion that growth differentiation factor 11 (GDF11) acts as a rejuvenation factor has remained controversial. However, in addition to its role in aging, the relationship between GDF11 and cerebral ischemia is still an… read more here.
Keywords: recovery; differentiation factor; cerebral ischemia; growth differentiation ... See more keywords
Growth and differentiation factor 15 is a biomarker for low back pain-associated disability.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.01.011
Abstract: The development of low back pain (LBP) is often associated with obesity and sarcopenia. However, the mechanisms of this association remain unclear. To clarify this, we measured circulating levels of a selected panel of soluble… read more here.
Keywords: back pain; differentiation factor; disability; low back ... See more keywords