Transcriptional regulation of neutrophil differentiation and function during inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ru1219-504rr
Abstract: Neutrophils are the most abundant leukocytes in innate immunity where they elicit powerful effector functions to eliminate invading pathogens and modulate the adaptive as well as the innate immune response. Neutrophil function must be tightly… read more here.
Keywords: differentiation function; neutrophil differentiation; function inflammation; function ... See more keywords
Role of chromatin modulator Dpy30 in osteoclast differentiation and function.
Sign Up to like & getrecommendations! Published in 2022 at "Bone"
DOI: 10.1016/j.bone.2022.116379
Abstract: Osteoclasts are the principal bone resorption cells crucial for homeostatic bone remodeling and pathological bone destruction. Increasing data demonstrate a vital role of histone methylation in osteoclastogenesis. As an integral core subunit of H3K4 methyltransferases,… read more here.
Keywords: bone; differentiation; differentiation function; dpy30 ... See more keywords
Regulation of T cell differentiation and function by ubiquitin-specific proteases.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2019.103922
Abstract: T cells play critical roles in immune responses to pathogens, autoimmunity, and antitumor immunity. During the past few decades, increasing numbers of studies have demonstrated the significance of protein ubiquitination in T cell-mediated immunity. Several… read more here.
Keywords: specific proteases; cell differentiation; ubiquitin specific; differentiation function ... See more keywords
D(-)-salicin inhibits RANKL-induced osteoclast differentiation and function in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Fitoterapia"
DOI: 10.1016/j.fitote.2021.104981
Abstract: Osteoporosis is a disease, which causes huge economic and social burden. Using natural compound to treat such disease is beneficial for the fewer side effects and effectiveness. D-(-)-salicin (DSA) is a component extracted from the… read more here.
Keywords: osteoclast differentiation; dsa; differentiation function; rankl induced ... See more keywords
Distinct metabolic pathways mediate regulatory T cell differentiation and function.
Sign Up to like & getrecommendations! Published in 2020 at "Immunology letters"
DOI: 10.1016/j.imlet.2020.04.011
Abstract: Investigation of the cellular metabolic pathways of immune cells, or immunometabolism, is a field of increasing interest. An understanding of immunometabolism provides routes to modifying T cell function for therapeutic purposes. Here, we review immunometabolism… read more here.
Keywords: metabolic pathways; differentiation function; function; cell ... See more keywords
Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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DOI: 10.1016/j.isci.2021.103235
Abstract: Summary Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of… read more here.
Keywords: conditions maintenance; differentiation function; maintenance hepatocyte; phh ... See more keywords
Adipose tissue regulatory T cells: differentiation and function.
Sign Up to like & getrecommendations! Published in 2022 at "International reviews of immunology"
DOI: 10.1080/08830185.2022.2044808
Abstract: Rising obesity levels, worldwide, are resulting in substantial increases in cardiovascular disease, diabetes, kidney disease, musculoskeletal disorders, and certain cancers, and obesity-associated illnesses are estimated to cause ∼4 million deaths worldwide per year. A common… read more here.
Keywords: differentiation function; adipose tissue; regulatory cells;
The effect of statins on the differentiation and function of central nervous system cells.
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230308121645
Abstract: Statins (3-hydroxy-3-methylglutaryl-CoA reductase inhibitors) reduce plasma cholesterol and improve endothelium-dependent vasodilation, inflammation, and oxidative stress. The effect of statins on the central nervous system (CNS), particularly on cognition and neurological disorders such as cerebral ischemic… read more here.
Keywords: system; central nervous; effect statins; differentiation function ... See more keywords
Origin, Differentiation, and Function of Intestinal Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02733
Abstract: Macrophages are increasingly recognized as essential players in the maintenance of intestinal homeostasis and as key sentinels of the intestinal immune system. However, somewhat paradoxically, they are also implicated in chronic pathologies of the gastrointestinal… read more here.
Keywords: origin differentiation; differentiation function; intestinal macrophages; function intestinal ... See more keywords
Signaling networks controlling ID and E protein activity in T cell differentiation and function
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.964581
Abstract: E and inhibitor of DNA binding (ID) proteins are involved in various cellular developmental processes and effector activities in T cells. Recent findings indicate that E and ID proteins are not only responsible for regulating… read more here.
Keywords: cell; function; differentiation function; biology ... See more keywords
Inhibitory Effect of Cudratrixanthone U on RANKL-Induced Osteoclast Differentiation and Function in Macrophages and BMM Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01048
Abstract: Cudratrixanthone U (CTU) is a prenylated xanthone compound isolated from Maclura tricuspidata Bureau (Moraceae). Prenylated xanthones have been reported to exhibit a variety of biological activities. However, the effects of prenylated xanthone on osteoclast differentiation… read more here.
Keywords: bmm cells; osteoclast differentiation; macrophages bmm; differentiation function ... See more keywords