CHAF1B Overexpression: A Brake for the Differentiation of Leukemia Cells.
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DOI: 10.1016/j.ccell.2018.10.011
Abstract: In this issue of Cancer Cell, Volk et al. report that overexpression of CHAF1B displaces myeloid transcription factors from chromatin, and deletion of CHAF1B promotes differentiation of leukemia cells and suppresses leukemogenesis in a murine model,… read more here.
Keywords: leukemia cells; differentiation leukemia; chaf1b overexpression;