Articles with "differentiation leukemic" as a keyword



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SMARCD1 negatively regulates myeloid differentiation of leukemic cells via epigenetic mechanisms

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Published in 2022 at "Blood Advances"

DOI: 10.1182/bloodadvances.2021006235

Abstract: Aberrations in transcription and epigenetic factors lead to neoplastic transformation such as acute myeloid leukemia (AML), which is characterized by accumulation of hyperproliferative blasts originating from leukemic stem cells. The use of therapeutic agents designed… read more here.

Keywords: smarcd1 negatively; negatively regulates; differentiation leukemic; regulates myeloid ... See more keywords