TNF-α suppresses osteogenic differentiation of MSCs by accelerating P2Y2 receptor in estrogen-deficiency induced osteoporosis.
Sign Up to like & getrecommendations! Published in 2018 at "Bone"
DOI: 10.1016/j.bone.2018.09.012
Abstract: Tumor Necrosis Factor-α (TNF-α)-inhibited osteogenic differentiation of mesenchymal stem cells (MSCs) contributes to impaired bone formation, which plays a central role in the pathogenesis of postmenopausal osteoporosis. However, the exact mechanisms of TNF-α-inhibited osteoblast differentiation… read more here.
Keywords: receptor; p2y2 receptor; tnf; differentiation mscs ... See more keywords
UHRF1 associated with osteogenic differentiation of MSCs contributes to osteosarcoma progression and has clinical prognostic impact in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021041503
Abstract: Ubiquitin-like with plant homeodomain and ring finger domains 1 (UHRF1) can mediate DNA methylation and histone modifications in the epigenetic regulation of gene expression, stem cell differentiation and tumorigenesis. Here, we analyzed the differentially expressed… read more here.
Keywords: differentiation; differentiation mscs; osteosarcoma progression; osteosarcoma ... See more keywords
MiR-374b promotes osteogenic differentiation of MSCs by degrading PTEN and promoting fracture healing.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201806_15149
Abstract: OBJECTIVE To investigate whether miR-374b can promote the differentiation of MSCs into osteoblasts by mediating PTEN, thus promoting fracture healing. MATERIALS AND METHODS Primary cultured mouse mesenchymal stem cells were obtained for following experiments. Flow… read more here.
Keywords: mir 374b; differentiation mscs; promoting fracture; mscs ... See more keywords