Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15599
Abstract: The ability to quantify differentiation potential of single cells is a task of critical importance. Here we demonstrate, using over 7,000 single-cell RNA-Seq profiles, that differentiation potency of a single cell can be approximated by… read more here.
Keywords: single cell; cell; differentiation potency; entropy ... See more keywords
Characterizing Cellular Differentiation Potency and Waddington Landscape via Energy Indicator
Sign Up to like & getrecommendations! Published in 2023 at "Research"
DOI: 10.34133/research.0118
Abstract: The precise characterization of cellular differentiation potency remains an open question, which is fundamentally important for deciphering the dynamics mechanism related to cell fate transition. We quantitatively evaluated the differentiation potency of different stem cells… read more here.
Keywords: cellular differentiation; energy; cell; differentiation potency ... See more keywords