Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
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DOI: 10.1016/j.ejmech.2017.11.066
Abstract: Myeloid differentiation protein 2 (MD2) is an essential molecule which recognizes lipopolysaccharide (LPS), leading to initiation of inflammation through the activation of Toll-like receptor 4 (TLR4) signaling. Caffeic acid phenethyl ester (CAPE) from propolis of… read more here.
Keywords: caffeic acid; differentiation protein; phenethyl ester; myeloid differentiation ... See more keywords