Advances in differentiation therapy for osteosarcoma.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.08.010
Abstract: Differentiation therapy involves the use of agents that can induce differentiation in cancer cells, with the irreversible loss of tumour phenotype. The application of differentiation therapy in osteosarcoma has made progress because of a better… read more here.
Keywords: differentiation therapy; differentiation; advances differentiation; therapy osteosarcoma ... See more keywords
2000 - MONOLINEAGE ORIGIN OF RELAPSE FOLLOWING MULTILINEAGE DIFFERENTIATION THERAPY OF ACUTE MYELOID LEUKEMIA
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DOI: 10.1016/j.exphem.2019.06.275
Abstract: Acute myeloid leukaemia (AML) is characterized by the accumulation of transformed immature myeloid blasts. While most AML patients treated with standard therapy have poor outcomes, in the APL disease subtype retinoic acid induces leukaemia maturation… read more here.
Keywords: acute myeloid; therapy; differentiation; differentiation therapy ... See more keywords
Non‐genetic heterogeneity, altered cell fate and differentiation therapy
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DOI: 10.15252/emmm.202012670
Abstract: Altered capacity for self‐renewal and differentiation is a hallmark of cancer, and many tumors are composed of cells with a developmentally immature phenotype. Among the malignancies where processes that govern cell fate decisions have been… read more here.
Keywords: genetic heterogeneity; non genetic; differentiation; cell fate ... See more keywords